Holtgrave E A
Poliklinik für Kieferorthopadie der Freien Universität Berlin.
Dtsch Zahnarztl Z. 1990 Aug;45(8):469-72.
The present study examined the role of the innermost layer of dental sac tissue in periodontal development. Empty bony crypts were filled with Hydroxylapatite ceramic granules of porous consistency in 5-day-old rats. After 4.5 and 24 weeks the specimens were processed for light and transmission electron microscopy. Only 4 weeks later cement regeneration was seen on ceramic surfaces with bundles of oriented collagen fibers inserting in the cementoid matrix. Ultrastructurally the newly formed cementum-like tissue was in intimate contact to the synthetic hydroxylapatite crystals. A consistent finding was the presence of an interface between cementum and the ceramic surface. The present findings question the unique role of the "investing layer" in periodontal development and the existence of cement-inducting properties of dentin.
本研究探讨了牙囊组织最内层在牙周发育中的作用。在5日龄大鼠的空骨隐窝中填充具有多孔结构的羟基磷灰石陶瓷颗粒。4.5周和24周后，对标本进行光镜和透射电镜处理。仅4周后，在陶瓷表面可见牙骨质再生，有束状定向胶原纤维插入牙骨质样基质中。超微结构显示，新形成的类牙骨质组织与合成羟基磷灰石晶体紧密接触。一个一致的发现是牙骨质与陶瓷表面之间存在界面。本研究结果对“覆盖层”在牙周发育中的独特作用以及牙本质诱导牙骨质形成特性的存在提出了质疑。
