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非惊厥性癫痫持续状态的治疗。

Treatment of nonconvulsive status epilepticus.

机构信息

KS 479 Neurology Department, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA, 02215, USA,

出版信息

Curr Treat Options Neurol. 2012 Aug;14(4):307-21. doi: 10.1007/s11940-012-0179-4.

Abstract

Status epilepticus is a neurologic emergency with significant potential morbidity and even mortality. It should be diagnosed and treated as quickly as possible, with concurrent rapid identification of the underlying cause. Nonconvulsive status epilepticus can be difficult to diagnose due to its protean manifestations, so a high index of suspicion is vital to prompt diagnosis and effective management. There are several different types and syndromes of nonconvulsive status epilepticus, and appropriate treatment varies according to those types. Some are relatively benign. Others, particularly the nonconvulsive status encountered in sick, hospitalized patients, can be life-threatening. The latter should be treated much more rapidly and aggressively than the former, sometimes even requiring coma-inducing anesthetic agents.

摘要

癫痫持续状态是一种具有显著潜在发病率甚至死亡率的神经急症。它应该尽快得到诊断和治疗,同时快速确定潜在的病因。由于其多变的表现,非惊厥性癫痫持续状态可能难以诊断,因此高度怀疑是及时诊断和有效治疗的关键。非惊厥性癫痫持续状态有几种不同的类型和综合征,治疗方法因类型而异。有些相对良性。其他的,特别是在患病住院的患者中出现的非惊厥性癫痫持续状态,可能会危及生命。后者的治疗应该比前者更加迅速和积极,有时甚至需要使用诱导昏迷的麻醉剂。

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