Pediatric Intensive Care Unit, Department of Emergency and Intensive Care, University Hospital "A. Gemelli", Catholic University of the Sacred Heart, Rome, Italy.
Eur J Pediatr. 2012 Dec;171(12):1855-7. doi: 10.1007/s00431-012-1769-6. Epub 2012 Jun 13.
Hypothermia may reduce the CO(2) production by decreasing the metabolism of the cooled tissue. We describe the first clinical use of hypothermia to lower hypercarbia in a case of bronchiolitis related respiratory failure unresponsive to maximal respiratory support. In this case, hypothermia allowed sparing the use of extracorporeal life support. Conclusion Hypothermia might be useful for severe acute respiratory failure unresponsive to aggressive respiratory support.
低温可能通过降低冷却组织的代谢来减少 CO2 的产生。我们描述了首例使用低温治疗因细支气管炎导致呼吸衰竭而对最大呼吸支持无反应的患者的高碳酸血症。在这种情况下,低温可避免使用体外生命支持。结论低温可能对严重的急性呼吸衰竭,对积极的呼吸支持无反应的情况下有用。