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由PVL-MRSA引起的复发性皮肤脓肿。

Recurrent cutaneous abscesses caused by PVL-MRSA.

作者信息

Antonelou Marilina, Knowles Jonathan, Siddiqi Shahab, Sharma Parveen

机构信息

Department of General Surgery/Care of the Elderly/Intensive Care and Urology, Barnet and Chase Farm Hospital, London, UK.

出版信息

BMJ Case Rep. 2011 Jun 29;2011:bcr0120113680. doi: 10.1136/bcr.01.2011.3680.

DOI:10.1136/bcr.01.2011.3680
PMID:22693181
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3128329/
Abstract

A 41-year-old female presented with a superficial buttock abscess. In the preceding 6 months she had four other abscesses at different anatomical sites. Screening for diabetes and immunocompromise was negative. Review of microbiology revealed Methicillin resistant Staphylococcus aureus harbouring Panton-Valentine leukocidin (PVL) genes. PVL syndrome is an emerging disorder associated with recurrent necrotic skin lesions in the young, otherwise healthy population.

摘要

一名41岁女性因臀部浅表脓肿就诊。在之前的6个月里，她在不同解剖部位出现了另外4个脓肿。糖尿病和免疫功能低下筛查均为阴性。微生物学检查发现耐甲氧西林金黄色葡萄球菌携带杀白细胞素（PVL）基因。PVL综合征是一种在年轻、健康人群中出现的与复发性坏死性皮肤病变相关的新疾病。

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Recurrent cutaneous abscesses caused by PVL-MRSA.由PVL-MRSA引起的复发性皮肤脓肿。
BMJ Case Rep. 2011 Jun 29;2011:bcr0120113680. doi: 10.1136/bcr.01.2011.3680.
2
Necrotizing pneumonia caused by Panton-Valentine leukocidin-producing methicillin-susceptible Staphylococcus aureus (MSSA).由产杀白细胞素的甲氧西林敏感金黄色葡萄球菌（MSSA）引起的坏死性肺炎。
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3
Panton-Valentine leukocidin-producing methicillin-Sensitive Staphylococcus aureus as a cause for recurrent, contagious skin infections in young, healthy travelers returned from a tropical country: a new worldwide public health problem?产生杀白细胞素的对甲氧西林敏感的金黄色葡萄球菌作为从热带国家归来的年轻健康旅行者反复发生传染性皮肤感染的病因：一个新的全球公共卫生问题？
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[Necrotizing fasciitis due to community-acquired panton-valentine leukocidin methicillin resistant Staphylococcus aureus].社区获得性杀白细胞素耐药性金黄色葡萄球菌所致坏死性筋膜炎
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本文引用的文献

1
Global distribution and evolution of Panton-Valentine leukocidin-positive methicillin-susceptible Staphylococcus aureus, 1981-2007.1981-2007 年间，对泛耐药性金黄色葡萄球菌（Panton-Valentine leukocidin-positive methicillin-susceptible Staphylococcus aureus）的全球分布和进化情况的研究。
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Brain abscess due to Panton-Valentine leukocidin-positive Staphylococcus aureus.由杀白细胞素阳性的金黄色葡萄球菌引起的脑脓肿。
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Clinical immunology review series: an approach to the patient with recurrent superficial abscesses.临床免疫学综述系列：复发性浅表脓肿患者的诊治方法
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Panton-Valentine leukocidin-producing methicillin-Sensitive Staphylococcus aureus as a cause for recurrent, contagious skin infections in young, healthy travelers returned from a tropical country: a new worldwide public health problem?产生杀白细胞素的对甲氧西林敏感的金黄色葡萄球菌作为从热带国家归来的年轻健康旅行者反复发生传染性皮肤感染的病因：一个新的全球公共卫生问题？
J Travel Med. 2008 Mar-Apr;15(2):137-9. doi: 10.1111/j.1708-8305.2008.00194.x.
5
Fulminant methicillin-sensitive Staphylococcus aureus infection in a healthy adolescent, highlighting 'Panton-Valentine leucocidin syndrome'.一名健康青少年的暴发性对甲氧西林敏感的金黄色葡萄球菌感染，凸显“杀白细胞素潘顿-瓦伦丁综合征”
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Panton-Valentine leukocidin genes are associated with enhanced inflammatory response and local disease in acute hematogenous Staphylococcus aureus osteomyelitis in children.潘顿-瓦伦丁杀白细胞素基因与儿童急性血源性金黄色葡萄球菌骨髓炎中炎症反应增强及局部病变相关。
Pediatrics. 2006 Feb;117(2):433-40. doi: 10.1542/peds.2005-0566.
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Community-acquired meticillin-resistant Staphylococcus aureus: an emerging threat.社区获得性耐甲氧西林金黄色葡萄球菌：一种新出现的威胁。
Lancet Infect Dis. 2005 May;5(5):275-86. doi: 10.1016/S1473-3099(05)70112-2.
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Community-acquired methicillin-resistant Staphylococcus aureus skin infection: an emerging clinical problem.
J Am Acad Dermatol. 2004 Feb;50(2):277-80. doi: 10.1016/j.jaad.2003.06.005.
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Staphylococcal pore-forming toxins.葡萄球菌成孔毒素
Curr Top Microbiol Immunol. 2001;257:53-83. doi: 10.1007/978-3-642-56508-3_4.
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Phage conversion of Panton-Valentine leukocidin in Staphylococcus aureus: molecular analysis of a PVL-converting phage, phiSLT.金黄色葡萄球菌中潘顿-瓦伦丁杀白细胞素的噬菌体转化：PVL转化噬菌体phiSLT的分子分析
Gene. 2001 May 2;268(1-2):195-206. doi: 10.1016/s0378-1119(01)00390-0.