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具有MRI表现的非典型狂犬病:诊断线索

Atypical rabies with MRI findings: clue to the diagnosis.

作者信息

Vaish Arvind Kumar, Jain Nirdesh, Gupta Lokesh Kumar, Verma Sudhir Kumar

机构信息

Department of Internal Medicine, CSM Medical University, Lucknow, India.

出版信息

BMJ Case Rep. 2011 Jun 29;2011:bcr0520114234. doi: 10.1136/bcr.05.2011.4234.

Abstract

Rabies is known for most as a fatal infectious disease, mainly transmitted to both humans and animals through bites by rabid animals. In its classical form, rabies is well recognised, but when it presents atypically in paralytic form, it may become difficult to distinguish from Guillain-Barré syndrome (GBS) or myelitis, particularly where history is not forthcoming or concealed. The authors report here an atypical case of paralytic rabies presenting with descending paralysis followed by furious form where clue to suspicion was MRI findings. Imaging in rabies is seldom done. MRI findings of rabies encephalitis are well known, but in myelitis these need to be further characterised. The authors present MRI findings in a confirmed case of rabies myelitis. The differential diagnosis of the imaging findings as well as the role and the relevance of imaging in the diagnosis of this disease are discussed.

摘要

狂犬病最为人所知的是一种致命的传染病,主要通过感染狂犬病的动物咬伤传播给人类和动物。在其典型形式中,狂犬病很容易识别,但当它以麻痹形式非典型出现时,可能难以与吉兰-巴雷综合征(GBS)或脊髓炎区分开来,特别是在病史不详或被隐瞒的情况下。作者在此报告一例非典型麻痹性狂犬病病例,该病例先出现下行性麻痹,随后出现狂暴型,怀疑的线索是MRI检查结果。狂犬病很少进行影像学检查。狂犬病脑炎的MRI表现是众所周知的,但在脊髓炎中,这些表现需要进一步明确。作者展示了一例确诊的狂犬病脊髓炎的MRI检查结果。讨论了影像学检查结果的鉴别诊断以及影像学在该疾病诊断中的作用和相关性。

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