Zeitlhofer J, Steiner M, Bousek K, Fitzal S, Asenbaum S, Wolner E, Deecke L
University Clinic of Neurology, Vienna, Austria.
Eur Neurol. 1990;30(5):284-90. doi: 10.1159/000117382.
Somatosensory-evoked potentials (SEPs) after median nerve stimulation were recorded in 10 neurologically normal patients during cardiopulmonary bypass and hypothermia. In all patients the changes of the latencies (spinal N13, cortical N20 and N35) and the central conduction time during cooling, and the decrease in latencies during rewarming was described by a gamma function. The analytic discussion of pooled data of all patients led to another SEP-latency-temperature relationship than the observation of each single patient. In 6 of 10 patients there was found a maximum of latency increase before the minimal temperature was reached. The cooling and the rewarming curve had to be considered separately. Latency changes of SEPs during hypothermia are discussed as a very complex phenomenon influenced by many technical and patient factors. This reduces the value of SEPs as an index of central nervous system integrity during open heart surgery and hypothermia.
在10名神经功能正常的患者进行体外循环和低温治疗期间，记录了正中神经刺激后的体感诱发电位（SEP）。在所有患者中，冷却期间潜伏期（脊髓N13、皮层N20和N35）和中枢传导时间的变化，以及复温期间潜伏期的缩短，均可用伽马函数来描述。对所有患者汇总数据的分析讨论得出的SEP潜伏期-温度关系，与对每位患者的观察结果不同。10名患者中有6名在达到最低温度之前潜伏期增加到最大值。冷却曲线和复温曲线必须分别考虑。低温期间SEP的潜伏期变化被认为是一个非常复杂的现象，受许多技术和患者因素的影响。这降低了SEP作为心脏直视手术和低温治疗期间中枢神经系统完整性指标的价值。
