Du Yan, Zhao Lijie, Feng Yi, Xu Desheng, Li Xiaohai, Wang Songtao
Engineering Research Center of Modem Preparation Technology of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Zhongguo Zhong Yao Za Zhi. 2012 Mar;37(5):589-93.
To characterize the flowability of traditional Chinese medicine (TCM) powders by using appropriate methods.
With highly flowable direct compression excipients and Chinese traditional medicine powder as raw materials, the flowability of material powders is determined by the Carr method and the Jenike method.
The Carr method and the Jenike method for the determination of the flowability of Chinese herb extract powder and direct-pressing excipients have no obvious difference. But the flowability of Chinese herb extract powder is not as good as direct compression excipients.
From the characterization results of both methods, we can find that the Carr method better reflects the actual flowability of TCM extracts, while the Jenike method can be used for guiding the design of the hopper device.
采用合适的方法表征中药粉末的流动性。
以高流动性的直接压片辅料和中药粉末为原料，采用卡尔指数法和詹尼克法测定物料粉末的流动性。
卡尔指数法和詹尼克法测定中药提取物粉末与直接压片辅料的流动性无明显差异。但中药提取物粉末的流动性不如直接压片辅料。
从两种方法的表征结果可知，卡尔指数法能更好地反映中药提取物的实际流动性，而詹尼克法可用于指导料斗装置的设计。
