Semler B L, Perrault J, Holland J J
Nucleic Acids Res. 1979 Aug 24;6(12):3923-31. doi: 10.1093/nar/6.12.3923.
We have determined the nucleotide sequence for the first 50 nucleotides at the 5' terminus of vesicular stomatitis virus (VSV) genome RNA. This sequence is identical to that of the in vitro RNA polymerase product synthesized by defective interfering (DI) particles of VSV. These results confirm previous conclusions rengarding DI and standard viral terminal sequences based on hybridization studies and earlier sequencing of the DI polymerase product RNA.
我们已经确定了水疱性口炎病毒(VSV)基因组RNA 5'末端前50个核苷酸的核苷酸序列。该序列与由VSV缺陷干扰(DI)颗粒合成的体外RNA聚合酶产物的序列相同。这些结果证实了先前基于杂交研究和DI聚合酶产物RNA早期测序得出的关于DI和标准病毒末端序列的结论。