Department of Psychology and Logopedics, Abo Akademi University, Turku, Finland.
Clin Neuropsychol. 2012;26(6):909-25. doi: 10.1080/13854046.2012.697192. Epub 2012 Jun 14.
Free recall memory deficits are common at early stages of Parkinson's disease (PD). As most studies have used intentional memory tasks, there is little information on how non-intentional, incidental encoding conditions affect memory performance in PD. We studied possible differences between PD patients and controls on free recall using incidental and intentional visual memory tasks. Free recall was examined in relation to attentive/executive functioning and subjective memory complaints. A total of 29 non-demented, medicated PD patients (age 60, disease duration 19 months) and 29 healthy controls (age 61) participated in the study. Incidental free recall was studied using a memory-modification of the Boston naming test (Memo-BNT) and intentional free recall with the 20 Objects test. There was a significant main effect for group due to worse free recall performances in the PD group. No statistically significant interaction between group and encoding condition was observed. The free recall deficit in the PD group was related to cognitive/psychomotor slowing, but not to attentive/executive task demands, or to subjective memory complaints. The results indicate that PD patients are impaired on free recall irrespective of encoding condition.
在帕金森病（PD）的早期阶段，自由回忆记忆缺陷很常见。由于大多数研究都使用了有意记忆任务，因此对于非有意的、偶然的编码条件如何影响 PD 患者的记忆表现，信息很少。我们研究了使用偶然和有意的视觉记忆任务时，PD 患者和对照组之间在自由回忆方面可能存在的差异。自由回忆与注意/执行功能和主观记忆抱怨有关。共有 29 名非痴呆、服药的 PD 患者（年龄 60 岁，病程 19 个月）和 29 名健康对照者（年龄 61 岁）参加了这项研究。使用记忆修正波士顿命名测验（Memo-BNT）研究偶然的自由回忆，使用 20 个物体测验研究有意的自由回忆。由于 PD 组的自由回忆表现较差，因此存在显著的组间主要效应。组和编码条件之间没有观察到统计学上显著的交互作用。PD 组的自由回忆缺陷与认知/心理运动减速有关，但与注意/执行任务需求或主观记忆抱怨无关。研究结果表明，无论编码条件如何，PD 患者的自由回忆都会受到损害。
