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心房颤动:老年患者非意外跌倒的独立危险因素。

Atrial fibrillation: an independent risk factor for nonaccidental falls in older patients.

作者信息

Sanders Natalie A, Ganguly Joya A, Jetter Tawni L, Daccarett Marcos, Wasmund Stephen L, Brignole Michelino, Hamdan Mohamed H

机构信息

Division of Geriatrics, University of Utah, Medical Center, Salt Lake City, Utah, USA.

出版信息

Pacing Clin Electrophysiol. 2012 Aug;35(8):973-9. doi: 10.1111/j.1540-8159.2012.03443.x. Epub 2012 Jun 13.

Abstract

BACKGROUND

Nonaccidental falls are often the result of a combination of factors including cardiovascular disorders such as orthostatic hypotension and unspecified cardiac arrhythmias. The objective of this study was to determine if there is an association between atrial fibrillation (AF) and nonaccidental falls.

METHODS

We reviewed the records of 442 consecutive patients >65 years old who presented to the Emergency Department at the University of Utah Medical Center with a complaint of fall.

RESULTS

Two-hundred eleven patients presented with nonaccidental fall, 231 patients with accidental fall. Patients with nonaccidental fall were more likely to be older, have a history of hypertension and neurological disorders, and taking five or more medications when compared to patients with accidental fall. Despite a similar prevalence of sinus rhythm at presentation, the prevalence of a history of AF was significantly higher in patients with nonaccidental fall compared to patients with accidental fall (26% vs 15%; P = 0.003). After adjusting for clinically and statistically significant predictors with a multivariate logistic regression analysis, AF, neurological disorders, and age ≤81 years were independent predictors of nonaccidental fall. In patients ≤81 years old (median age), the risk of nonaccidental falls was 2.5 times greater in patients with a history of AF when compared to those without a history of AF (odds ratio = 2.53 [confidence interval 95% 1.3-5], P = 0.007).

CONCLUSION

AF is an independent risk factor for nonaccidental falls. Our results emphasize the need to screen for AF in patients presenting with nonaccidental fall.

摘要

背景

非意外跌倒通常是多种因素共同作用的结果,包括心血管疾病,如体位性低血压和未明确的心律失常。本研究的目的是确定心房颤动(AF)与非意外跌倒之间是否存在关联。

方法

我们回顾了连续442例年龄>65岁、因跌倒主诉就诊于犹他大学医学中心急诊科的患者记录。

结果

211例患者为非意外跌倒,231例患者为意外跌倒。与意外跌倒患者相比,非意外跌倒患者年龄更大,有高血压和神经系统疾病史,且服用五种或更多药物。尽管就诊时窦性心律的患病率相似,但非意外跌倒患者的房颤病史患病率显著高于意外跌倒患者(26%对15%;P = 0.003)。在通过多因素逻辑回归分析对临床和统计学上有显著意义的预测因素进行校正后,房颤、神经系统疾病和年龄≤81岁是非意外跌倒的独立预测因素。在年龄≤81岁(中位年龄)的患者中,有房颤病史的患者非意外跌倒的风险是无房颤病史患者的2.5倍(比值比 = 2.53 [95%置信区间1.3 - 5],P = 0.007)。

结论

房颤是非意外跌倒的独立危险因素。我们的结果强调了对非意外跌倒患者进行房颤筛查的必要性。

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