Tralman G, Andrianov V, Arend A, Männik P, Kibur R T, Nõupuu K, Uksov D, Aunapuu M
Small Animal Clinic Billy, Tallinn, Estonia.
Anat Histol Embryol. 2013 Apr;42(2):80-9. doi: 10.1111/j.1439-0264.2012.01167.x. Epub 2012 Jun 14.
The study compares the efficiency of a new bone fixator combining periostal and intramedullary osteosynthesis to bone plating in treatment of tibial fractures in sheep. Experimental osteotomies were performed in the middle third of the left tibia. Animals were divided into two groups: in one group (four animals) combined osteosynthesis (rod-through-plate fixator, RTP fixator) was applied, and in the other group (three animals) bone plating was used. The experiments lasted for 10 weeks during which fracture union was followed by radiography, and the healing process was studied by blood serum markers reflecting bone turnover and by histological and immunohistochemical investigations. In the RTP fixator group, animals started to load body weight on the operated limbs the next day after the surgery, while in the bone plating group, this happened only on the seventh day. In the RTP fixator group, consolidation of fractures was also faster, as demonstrated by radiographical, histological, and immunohistochemical investigations and in part by blood serum markers for bone formation. It can be concluded that application of RTP fixation is more efficient than plate fixation in the treatment of experimental osteotomies of long bones in sheep.
本研究比较了一种结合骨膜和髓内骨固定术的新型骨固定器与接骨板在治疗绵羊胫骨骨折方面的效率。在左胫骨中部三分之一处进行实验性截骨术。将动物分为两组：一组（四只动物）采用联合骨固定术（穿板棒式固定器，RTP固定器），另一组（三只动物）使用接骨板。实验持续10周，在此期间通过X线摄影跟踪骨折愈合情况，并通过反映骨转换的血清标志物以及组织学和免疫组织化学研究来研究愈合过程。在RTP固定器组中，动物在手术后第二天开始在手术肢体上负重，而在接骨板组中，直到第七天才开始负重。如X线摄影、组织学和免疫组织化学研究以及部分骨形成血清标志物所示，RTP固定器组骨折的愈合也更快。可以得出结论，在治疗绵羊长骨实验性截骨时，应用RTP固定比接骨板固定更有效。
