Chen Ran, Zhao Bo-Wen, Wang Bei, Tang Hai-Lin, Li Peng, Pan Mei, Xu Li-Long
Department of Diagnostic Ultrasound and Echocardiography, Sir Run Run Shaw Hospital, Zhejiang University College of Medicine and Sir Run Run Shaw Institute of Clinical Medicine of Zhejiang University, Hangzhou, China.
Echocardiography. 2012 Oct;29(9):1081-90. doi: 10.1111/j.1540-8175.2012.01737.x. Epub 2012 Jun 14.
A novel echocardiographic method, vector flow mapping (VFM), acquires velocity vector from color Doppler velocity data. The purpose of this study was to evaluate whether VFM could provide useful information on intracardiac flow and helpful to evaluate left ventricular (LV) function. Thirty-eight patients with uremia undergoing hemodialysis and 30 healthy volunteers were enrolled. The maximum vector velocity, maximum diameter and duration of the intracardiac vortex were measured using VFM software during systole and diastole. The maximum vector velocity of the vortex and the peak velocities at the basal septum and lateral mitral annulus measured by tissue Doppler imaging (TDI) were correlated. The maximum diameter and duration of vortex formation were significantly higher in uremic patients compared with the control group during the ejection phase (40.6 ± 7.9 cm/sec vs. 28.1 ± 3.9 cm/sec; 297.1 ± 22.1 msec vs. 145.4 ± 19.3 msec, all P < 0.001). The maximal diameters of the vortex were higher in uremic patients compared with the control group during diastole (25.6 ± 3.4 mm vs. 16.4 ± 2.1 mm; 34.3 ± 3.1 mm vs. 26.8 ± 3.9 mm; 37.5 ± 2.4 mm vs. 20.9 ± 2.1 mm; all P < 0.001). The maximum vector velocities were lower in mid-diastole and late diastole (23.6 ± 2.3 cm/sec vs. 45.2 ± 3.7 cm/sec; 31.9 ± 2.9 cm/sec vs. 54.7 ± 3.2 cm/sec, all P < 0.001). There was a correlation between the maximum vector velocity of the vortex in mid-diastole and E'/A' at the septum and lateral mitral annulus (r = 0.70, r = 0.76, P < 0.001). Vortex can be utilized to provide intracardiac dynamic information using VFM and it may be a good supplement for evaluating LV function.
一种新型超声心动图方法，即矢量血流图（VFM），可从彩色多普勒速度数据中获取速度矢量。本研究的目的是评估VFM是否能提供有关心内血流的有用信息，并有助于评估左心室（LV）功能。纳入了38例接受血液透析的尿毒症患者和30名健康志愿者。在收缩期和舒张期使用VFM软件测量心内涡流的最大矢量速度、最大直径和持续时间。将涡流的最大矢量速度与通过组织多普勒成像（TDI）测量的基底间隔和二尖瓣外侧环处的峰值速度进行相关性分析。在射血期，尿毒症患者的涡流最大直径和持续时间显著高于对照组（40.6±7.9厘米/秒对28.1±3.9厘米/秒；297.1±22.1毫秒对145.4±19.3毫秒，均P<0.001）。在舒张期，尿毒症患者的涡流最大直径高于对照组（25.6±3.4毫米对16.4±2.1毫米；34.3±3.1毫米对26.8±3.9毫米；37.5±2.4毫米对20.9±2.1毫米；均P<0.001）。舒张中期和舒张晚期的最大矢量速度较低（23.6±2.3厘米/秒对45.2±3.7厘米/秒；31.9±2.9厘米/秒对54.7±3.2厘米/秒，均P<0.001）。舒张中期涡流的最大矢量速度与间隔和二尖瓣外侧环处的E'/A'之间存在相关性（r=0.70，r=0.76，P<0.001）。利用VFM可以通过涡流提供心内动态信息，它可能是评估LV功能的良好补充。
