Department of Epidemiology and Biostatistics, School of Public Health, Peking University, No. 38 Xueyuan Road, Haidian District, Beijing 100191, People's Republic of China.
Arch Gynecol Obstet. 2012 Oct;286(4):905-11. doi: 10.1007/s00404-012-2403-6. Epub 2012 Jun 14.
We aimed to investigate the combined associations of prepregnancy body mass index (BMI) and gestational weight gain (GWG) with pregnancy outcomes in Chinese women.
Data for 292,568 singleton term pregnancies were selected from 1993 to 2005 based on the Perinatal Health Care Surveillance System, with anthropometric measurements being collected prospectively. Prepregnancy BMI was categorized according to the definitions of the World Health Organization (WHO). Total GWG was categorized into four groups. Adjusted associations of prepregnancy BMI and GWG with outcomes of interest were estimated using logistic regression analyses. GWG was categorized as below, within and above the Institute of Medicine (IOM) (2009) recommendations.
Maternal overweight and high GWG or GWG above the IOM recommendation were associated with hypertensive disorders complicating pregnancy, cesarean delivery, macrosomia and large-for-gestational-age (LGA) infants. Maternal underweight and low GWG or GWG below the IOM recommendation were risk factors for low-birth-weight (LBW) and small-for-gestational-age (SGA) infants. Moreover, being overweight [odds ratio (OR) 1.2, 95 % confidence interval (CI) 1.0-1.3) and having a low weight gain (OR 1.1, 95 % CI 1.0-1.1) increased the risk of newborn asphyxia.
Being overweight/obese and having a high weight gain, as well as being underweight and having a low weight gain, were associated with increased risks for adverse pregnancy outcomes in Chinese women.
我们旨在研究中国妇女孕前体重指数（BMI）和孕期体重增加（GWG）与妊娠结局的综合关联。
根据围产保健监测系统，从 1993 年至 2005 年选择了 292568 例单胎足月妊娠的数据，前瞻性收集人体测量数据。根据世界卫生组织（WHO）的定义对孕前 BMI 进行分类。将总 GWG 分为四组。使用逻辑回归分析估计孕前 BMI 和 GWG 与感兴趣结局的调整关联。GWG 被分类为低于、等于和高于医学研究所（IOM）（2009 年）建议。
母亲超重和 GWG 高或高于 IOM 建议与妊娠合并高血压疾病、剖宫产、巨大儿和大于胎龄儿（LGA）婴儿有关。母亲体重不足和 GWG 低或低于 IOM 建议是低出生体重（LBW）和小于胎龄儿（SGA）婴儿的危险因素。此外，超重[比值比（OR）1.2，95%置信区间（CI）1.0-1.3）和体重增加不足（OR 1.1，95%CI 1.0-1.1）增加了新生儿窒息的风险。
超重/肥胖和体重增加高，以及体重不足和体重增加低，与中国妇女不良妊娠结局的风险增加有关。
