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无症状阻生智齿的手术拔除与保留治疗

Surgical removal versus retention for the management of asymptomatic impacted wisdom teeth.

作者信息

Mettes Theodorus Dirk G, Ghaeminia Hossein, Nienhuijs Marloes E L, Perry John, van der Sanden Wil J M, Plasschaert Alphons

机构信息

Scientific Institute for Quality of Healthcare, Radboud University Nijmegen Medical Center, Nijmegen, Netherlands.

出版信息

Cochrane Database Syst Rev. 2012 Jun 13(6):CD003879. doi: 10.1002/14651858.CD003879.pub3.

Abstract

BACKGROUND

The prophylactic removal of asymptomatic impacted wisdom teeth is defined as the (surgical) removal of wisdom teeth in the absence of local disease. Impacted wisdom teeth may be associated with pathological changes, such as inflammation of the gums around the tooth, root resorption, gum and alveolar bone disease, damage to the adjacent teeth and the development of cysts and tumours. Other reasons to justify prophylactic removal have been to prevent late incisor crowding. When surgical removal is carried out in older patients, following the development of symptoms, the risk of postoperative complications, pain and discomfort increases. Nevertheless, in most developed countries prophylactic removal of trouble-free wisdom teeth, either impacted or fully erupted, has long been considered as 'appropriate care' and is a very common procedure. There is a need to determine whether there is evidence to support this practice.

OBJECTIVES

To evaluate the effects of prophylactic removal of asymptomatic impacted wisdom teeth in adolescents and adults compared with the retention (conservative management) of these wisdom teeth.

SEARCH METHODS

The following electronic databases were searched: the Cochrane Oral Health Group's Trials Register (to 30 March 2012), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2012, Issue 1), MEDLINE via OVID (1950 to 30 March 2012), and EMBASE via OVID (1980 to 30 March 2012). There were no restrictions on language or date of publication.

SELECTION CRITERIA

All randomised controlled trials (RCTs) on adolescents and adults comparing the effect of prophylactic removal of asymptomatic impacted wisdom teeth with no-treatment (retention).

DATA COLLECTION AND ANALYSIS

Six review authors screened the results of the search and assessed whether trials met the inclusion criteria for the review. Data extraction and risk of bias assessment were conducted in duplicate and independently by six review authors. Where information was unclear, authors of studies were contacted for additional information.

MAIN RESULTS

No RCTs were identified that compared the removal of asymptomatic wisdom teeth with retention and reported quality of life. One RCT on adolescents was identified that compared the removal of impacted mandibular wisdom teeth with retention and only examined the effect on late lower incisor crowding. This study at high risk of bias provided no evidence that extraction of wisdom teeth had an effect on lower incisor crowding over 5 years.

AUTHORS' CONCLUSIONS: Insufficient evidence was found to support or refute routine prophylactic removal of asymptomatic impacted wisdom teeth in adults. A single trial comparing removal versus retention found no evidence of a difference on late lower incisor crowding at 5 years, however no other relevant outcomes were measured.Watchful monitoring of asymptomatic third molar teeth may be a more prudent strategy.

摘要

背景

预防性拔除无症状阻生智齿被定义为在无局部疾病情况下(手术)拔除智齿。阻生智齿可能与病理变化相关,如牙齿周围牙龈炎症、牙根吸收、牙龈及牙槽骨疾病、邻牙损伤以及囊肿和肿瘤的发生。其他支持预防性拔除的理由是预防后期切牙拥挤。在老年患者出现症状后进行手术拔除时,术后并发症、疼痛和不适的风险会增加。然而,在大多数发达国家,预防性拔除无问题的智齿,无论是阻生还是完全萌出的,长期以来都被视为“适当的治疗”,并且是一种非常常见的手术。有必要确定是否有证据支持这种做法。

目的

评估与保留(保守治疗)无症状阻生智齿相比,预防性拔除青少年和成人无症状阻生智齿的效果。

检索方法

检索了以下电子数据库:Cochrane口腔健康组试验注册库(截至2012年3月30日)、Cochrane对照试验中心注册库(CENTRAL)(《Cochrane图书馆》2012年第1期)、通过OVID检索的MEDLINE(1950年至2012年3月30日)以及通过OVID检索的EMBASE(1980年至2012年3月30日)。对语言和出版日期没有限制。

选择标准

所有关于青少年和成人的随机对照试验(RCT),比较预防性拔除无症状阻生智齿与不治疗(保留)的效果。

数据收集与分析

六位综述作者筛选了检索结果,并评估试验是否符合综述的纳入标准。数据提取和偏倚风险评估由六位综述作者独立进行两次。如果信息不清楚,会联系研究作者获取更多信息。

主要结果

未发现将无症状智齿拔除与保留进行比较并报告生活质量的RCT。确定了一项关于青少年的RCT,该试验比较了拔除下颌阻生智齿与保留智齿的效果,且仅研究了对后期下切牙拥挤的影响。这项存在高偏倚风险的研究没有提供证据表明拔除智齿在5年内对下切牙拥挤有影响。

作者结论

没有足够的证据支持或反驳对成人无症状阻生智齿进行常规预防性拔除。一项比较拔除与保留的单一试验没有发现5年后在下切牙拥挤方面存在差异的证据,然而未测量其他相关结局。对无症状第三磨牙进行密切监测可能是一种更谨慎的策略。

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