Department of Otolaryngology-Head and Neck Surgery, Weill Cornell Medical College, New York, NY 10003, USA.
Int Forum Allergy Rhinol. 2012 Nov;2(6):453-9. doi: 10.1002/alr.21058. Epub 2012 Jun 13.
Nasal endoscopy is an important part of the clinical evaluation of patients with chronic rhinosinusitis. However, the objectivity and interrater agreement of the procedure related findings have not been well studied, especially in patients who have previously had sinus surgery.
Patients with a history of endoscopic sinus surgery for chronic rhinosinusitis were prospectively enrolled from a tertiary rhinology practice. Fourteen endoscopic nasal examinations were recorded using digital video capture software. Each patient also underwent computed tomography (CT) and completed the Sinonasal Outcome Test (SNOT-22). Blinded review of inflammatory and anatomic findings for each video was independently performed by 5 academic rhinologists at separate institutions. Comparisons were performed using the unweighted Fleiss' kappa statistic (K(f) ) and the prevalence- and bias-adjusted kappa (PABAK).
There were no significant correlations between age, Lund-Mackay score, or SNOT-22 score. Interrater agreement was variable across the characteristics studied. Mean PABAK was excellent for the assessment of polyps (K(f) = 0.886); moderate for the assessments of middle turbinate (MT) integrity (K(f) = 0.543), MT position (K(f) = 0.443), maxillary sinus patency (K(f) = 0.593), and ethmoid sinus patency (K(f) = 0.429); fair for discharge (K(f) = 0.314), synechiae (K(f) = 0.257), and middle meatus patency (K(f) = 0.229); and poor for MT mucosal changes (K(f) = 0.148) and uncinate process (K(f) = 0.126).
This study was notable for variability in the interrater agreement among the inflammatory and anatomic attributes that were examined. Further standardization of nasal endoscopy with regard to interpretation may improve the reliability of this procedure in clinical practice.
鼻内窥镜检查是慢性鼻-鼻窦炎患者临床评估的重要组成部分。然而,该程序相关发现的客观性和评分者间一致性尚未得到很好的研究,尤其是在既往鼻窦手术的患者中。
前瞻性地从一家三级鼻科诊所招募有慢性鼻-鼻窦炎内镜鼻窦手术史的患者。使用数字视频捕获软件记录了 14 次鼻内窥镜检查。每位患者还接受了计算机断层扫描(CT)并完成了鼻-鼻窦结局测试 22 项(SNOT-22)。5 位在不同机构的学术鼻科医生对每个视频的炎症和解剖学发现进行了盲法独立评估。使用非加权 Fleiss κ 统计量(K(f))和基于流行率和偏倚调整的 κ(PABAK)进行比较。
年龄、Lund-Mackay 评分或 SNOT-22 评分与评分者间一致性均无显著相关性。在研究的各项特征中,评分者间一致性各不相同。息肉评估的平均 PABAK 为优秀(K(f) = 0.886);中鼻甲(MT)完整性(K(f) = 0.543)、MT 位置(K(f) = 0.443)、上颌窦通畅(K(f) = 0.593)和筛窦通畅(K(f) = 0.429)评估为中度;分泌物(K(f) = 0.314)、黏连(K(f) = 0.257)和中鼻道通畅(K(f) = 0.229)评估为一般;MT 黏膜改变(K(f) = 0.148)和钩突(K(f) = 0.126)评估为差。
本研究的特点是所检查的炎症和解剖属性的评分者间一致性存在差异。进一步规范鼻内窥镜检查的解读可能会提高该程序在临床实践中的可靠性。