Hasan Mahboob, Kumar Amit
Department of Pathology, J N Medical College, AMU, Aligarh, India.
BMJ Case Rep. 2011 May 12;2011:bcr0120113750. doi: 10.1136/bcr.01.2011.3750.
A 10-year-old female presented with complaints of submandibular swelling, sore throat, painful deglutition, difficulty in speech and fever. The patient gave history of recurrent tonsillitis associated with snoring and breathing difficulty during sleep. Oral examination revealed inflamed, hypertrophied tonsils and dental caries. Throat swab culture was positive for β-haemolytic streptococci. The patient underwent elective tonsillectomy and histopathological examination revealed characteristic colonies of actinomycetes. The patient was put on intravenous penicillin and after 6 months of follow-up is disease free. The report recommends that histopathological examination must be performed in cases of recurrent tonsillitis with tonsillar hypertrophy. Microscopic examination may reveal actinomycetes which may not be evident on culture; treatment requires a longer course of high-dose penicillins. This further supports the view that actinomycetes have a causal association with recurrent tonsillitis and tonsillar hypertrophy.
一名10岁女性因下颌下肿胀、咽痛、吞咽疼痛、言语困难和发热前来就诊。患者有复发性扁桃体炎病史,伴有睡眠时打鼾和呼吸困难。口腔检查发现扁桃体发炎、肥大及龋齿。咽拭子培养显示β-溶血性链球菌阳性。患者接受了择期扁桃体切除术,组织病理学检查发现放线菌的特征性菌落。患者接受静脉注射青霉素治疗,随访6个月后无疾病复发。该报告建议,对于复发性扁桃体炎伴扁桃体肥大的病例,必须进行组织病理学检查。显微镜检查可能发现放线菌,而在培养时可能不明显;治疗需要较长疗程的大剂量青霉素。这进一步支持了放线菌与复发性扁桃体炎和扁桃体肥大存在因果关系的观点。