Bhargava D, Bhusnurmath B, Sundaram K R, Raman R, Al Okbi H M, Al Abri R, Date A
Department of Surgery ENT Division, Sultan Qaboos University Hospital, PO Box 38, Al Khod 123 Muscat, Oman.
Acta Trop. 2001 Oct 22;80(2):163-8. doi: 10.1016/s0001-706x(01)00172-3.
Actinomycosis has been known to involve virtually every anatomic site in the body. Although actinomycosis has been identified in resected tonsils, its possible role in adeno-tonsillar disease has received little attention. A clinicopathological study of 302 patients who had adeno-tonsillar surgery is presented. Tonsillar actinomycosis was present in 86 (28.5%) patients. The statistical analysis revealed a significant association (P<0.0001) of actinomycosis and tonsillar hypertrophy (56.8%) compared to only 10.3% in the recurrent tonsillitis group. A statistically significant association (P<0.0001) of tonsillar actinomycosis and sickle cell anaemia, beta thalassaemia, bronchial asthma and beta haemolytic streptococcal infections was also seen. This data supports a predisposition of the above conditions to tonsillar actinomycosis and adeno-tonsillar hypertrophy and a possible etiopathologic role of this organism in adeno-tonsillar hypertrophy and disease. Although the clinical association of actinomycosis and tonsillar hypertrophy and beta haemolytic streptococcal infection has been described before the association of actinomycosis with sickle cell anaemia, beta thalassaemia and bronchial asthma is being observed for the first time in literature.
放线菌病几乎可累及人体的每个解剖部位。尽管在切除的扁桃体中已发现放线菌病，但其在腺样体扁桃体疾病中的可能作用却很少受到关注。本文介绍了一项对302例行腺样体扁桃体手术患者的临床病理研究。86例（28.5%）患者存在扁桃体放线菌病。统计分析显示，与复发性扁桃体炎组仅10.3%相比，放线菌病与扁桃体肥大（56.8%）之间存在显著关联（P<0.0001）。扁桃体放线菌病与镰状细胞贫血、β地中海贫血、支气管哮喘和β溶血性链球菌感染之间也存在统计学显著关联（P<0.0001）。该数据支持上述疾病易患扁桃体放线菌病和腺样体扁桃体肥大，以及该病原体在腺样体扁桃体肥大和疾病中可能的病因学作用。尽管放线菌病与扁桃体肥大和β溶血性链球菌感染的临床关联此前已有描述，但放线菌病与镰状细胞贫血、β地中海贫血和支气管哮喘的关联在文献中首次被观察到。
