Amin Aliasger A, Reddy Anil, Jha Madan, Prasad Kolanu
Department of Surgery, James Cook University Hospital, Middlesbrough, UK.
BMJ Case Rep. 2011 May 12;2011:bcr0120113683. doi: 10.1136/bcr.01.2011.3683.
Metastasis to gastrointestinal (GI) tract from breast cancer is rare. Commonly affected organ in GI tract is stomach, followed by colon and then rectum. The authors report a case of a 61-year-old woman who had a mastectomy for lobular carcinoma of the breast 17 years ago and was referred to colorectal clinic with increased frequency of stools. Colonoscopy showed a stricture in the rectum, but biopsy was inconclusive. As she was symptomatic, she had a Hartmann's resection 5 months after she initially presented to the clinic. Histopathology of the resected specimen showed it to be metastasis from lobular carcinoma of the breast. Awareness of potential long delays in the presentation of metastatic breast cancer especially lobular carcinoma helps in the earlier diagnosis and clinical management.
乳腺癌转移至胃肠道罕见。胃肠道中最常受累的器官是胃,其次是结肠,然后是直肠。作者报告了一例61岁女性病例,该患者17年前因乳腺小叶癌接受了乳房切除术,现因排便次数增多转诊至结直肠诊所。结肠镜检查显示直肠有一处狭窄,但活检结果不明确。由于她有症状,在最初就诊于诊所5个月后接受了哈特曼切除术。切除标本的组织病理学检查显示为乳腺小叶癌转移。认识到转移性乳腺癌尤其是小叶癌的表现可能存在长时间延迟,有助于早期诊断和临床管理。