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原发性诊断 15 年后,乳腺癌转移至直肠。

Rectal metastasis from lobular breast carcinoma 15 years after primary diagnosis.

机构信息

Department of General Surgery, Asuncion Clinic, Tolosa, Guipúzcoa, Spain.

出版信息

Clin Transl Oncol. 2010 Feb;12(2):150-3. doi: 10.1007/S12094-010-0481-0.

Abstract

Lobular breast carcinoma represents 2-20% of infiltrative carcinomas of the breast. The incidence of extrahepatic gastrointestinal (GI) tract metastases observed in necropsy studies varies from 6% to 18% and the most commonly affected organ is the stomach, followed by colon and rectum [1-4]. Reported herein is the case of a 67-year-old woman who was primarily diagnosed and surgically treated for a lobular carcinoma of the breast 15 years ago and is now referred with back pain and right hydronephrosis caused by a metastasis in rectum. Frequently, the absence of specific symptoms of digestive metastases of breast cancer leads to a misdiagnosis of this pathology [5-7]. The treatment will be based on a detailed clinical history and histopathological findings. Metastases from breast cancer in GI tract tumours must be excluded in a patient with previous history of breast carcinoma, as in the case reported herein.

摘要

乳腺小叶癌占乳腺浸润性癌的 2-20%。尸检研究中观察到的肝外胃肠道(GI)转移的发生率为 6%至 18%,最常受影响的器官是胃,其次是结肠和直肠[1-4]。本文报告了一例 67 岁女性,15 年前因乳腺小叶癌被诊断并接受手术治疗,现因直肠转移引起腰痛和右侧肾积水就诊。通常,乳腺癌消化道转移缺乏特异性症状,导致对此类疾病的误诊[5-7]。治疗将基于详细的临床病史和组织病理学发现。对于有乳腺癌病史的患者,必须排除胃肠道肿瘤的乳腺癌转移,正如本文所报告的病例。

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