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应用凝血因子 XIII 成功治疗的过敏性紫癜结肠非典型肿瘤样受累

Atypical tumour-like involvement of the colon in Henoch-Schonlein purpura successfully treated with the administration of factor XIII.

作者信息

Ando Katuyoshi, Fujiya Mikihiro, Sugiyama Ryuji, Nata Toshie, Nomura Yoshiki, Ueno Nobuhiro, Kashima Shin, Ishikawa Chisato, Inaba Yuhei, Ito Takahiro, Moriichi Kentaro, Okamoto Kotaro, Ikuta Katsuya, Watari Jiro, Mizukami Yusuke, Kohgo Yutaka

机构信息

Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa, Japan.

出版信息

BMJ Case Rep. 2011 May 12;2011:bcr0820103251. doi: 10.1136/bcr.08.2010.3251.

Abstract

Henoch-Schönlein purpura (HSP) is a type of systemic vasculitis of the small vessels, which frequently involves the skin, kidney and gastrointestinal tract. While the typical intestinal features of HSP include diffuse mucosal redness, small ring-like petechiae and haemorrhagic erosions, tumour-like lesions are rarely observed. The current study presents a rare case of HSP with an intestinal tumour-like lesion in the caecum. The intestinal lesion caused fresh melaena, and was completely resolved with the administration of factor XIII as described in previously reported cases. It is important to immediately undergo proper treatment for improving tumour-like lesions which may cause severe complications, such as excessive haemorrhage and stricture.

摘要

过敏性紫癜(HSP)是一种小血管系统性血管炎,常累及皮肤、肾脏和胃肠道。虽然HSP典型的肠道表现包括弥漫性黏膜发红、小环状瘀点和出血性糜烂,但肿瘤样病变很少见。本研究报告了1例罕见的盲肠出现肿瘤样病变的HSP病例。该肠道病变导致新鲜黑便,如先前报道的病例所述,通过给予凝血因子XIII后完全缓解。对于可能导致严重并发症(如大出血和狭窄)的肿瘤样病变,立即进行适当治疗很重要。

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本文引用的文献

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