Alhajri Khalid, Alzerwi Nasser, Alsaleh Khalid, Yousef Hussam Bin, Alzaben Mohamed
Department of Surgery, Riyadh Military Hospital, Riyadh, Saudi Arabia.
BMJ Case Rep. 2011 May 12;2011:bcr1220103591. doi: 10.1136/bcr.12.2010.3591.
The development of disseminated (miliary) abdominal tuberculosis (TB) in patients following operations which affect their immunity, such as laparoscopic gastric bypass, is rare. The authors report the case of middle aged woman, who a few months after undergoing laparoscopic gastric bypass surgery for morbid obesity (body mass index 49), presented with generalised fatigability and abnormal liver function. A CT scan of the abdomen was suggestive of miliary TB. The patient developed acute abdomen pain. Intraoperative findings included perforated stomal ulcers at the gastrojejunostomy, diffuse micronodular involvement of the liver and spleen and thickened omentum. The perforation was closed and liver and omental biopsies were taken. Histology results from the liver and omentum revealed necrotising granulomatous inflammation suggestive of TB. Abdominal TB is a relatively rare manifestation of extrapulmonary TB. However, this diagnosis should be considered in patients immunocompromised due to immunosuppressive medication or operations affecting their nutrition. Early diagnosis and effective treatment of abdominal TB may decrease morbidity and mortality in such patients.
在接受影响免疫力的手术(如腹腔镜胃旁路手术)的患者中,播散性(粟粒性)腹部结核(TB)的发生较为罕见。作者报告了一例中年女性病例,该患者在因病态肥胖(体重指数49)接受腹腔镜胃旁路手术后数月,出现全身乏力和肝功能异常。腹部CT扫描提示粟粒性结核。患者出现急性腹痛。术中发现包括胃空肠吻合口处的吻合口溃疡穿孔、肝脏和脾脏弥漫性微小结节受累以及网膜增厚。穿孔被封闭,并取了肝脏和网膜活检。肝脏和网膜的组织学结果显示为坏死性肉芽肿性炎症,提示为结核。腹部结核是肺外结核相对罕见的表现形式。然而,对于因免疫抑制药物或影响营养的手术而免疫功能低下的患者,应考虑这一诊断。腹部结核的早期诊断和有效治疗可能会降低此类患者的发病率和死亡率。