UGA终止密码子在酵母线粒体中用作色氨酸密码子。
Use of the UGA terminator as a tryptophan codon in yeast mitochondria.
作者信息
Macino G, Coruzzi G, Nobrega F G, Li M, Tzagoloff A
出版信息
Proc Natl Acad Sci U S A. 1979 Aug;76(8):3784-5. doi: 10.1073/pnas.76.8.3784.
Abstract
We propose that the UGA terminator regularly occurs as a tryptophan codon in yeast mitochondrial DNA. This conclusion is based on the sequence analysis of mitochondrial DNA regions coding for structural genes of cytochrome b, cytochrome oxidase, and the ATPase.
摘要
我们提出，UGA终止密码子在酵母线粒体DNA中经常作为色氨酸密码子出现。这一结论是基于对编码细胞色素b、细胞色素氧化酶和ATP酶结构基因的线粒体DNA区域的序列分析得出的。
相似文献
1
Use of the UGA terminator as a tryptophan codon in yeast mitochondria.UGA终止密码子在酵母线粒体中用作色氨酸密码子。
Proc Natl Acad Sci U S A. 1979 Aug;76(8):3784-5. doi: 10.1073/pnas.76.8.3784.
2
Yeast mitochondrial tRNATrp can recognize the nonsense codon UGA.酵母线粒体色氨酸转运RNA能够识别无义密码子UGA。
Nature. 1980 Jun 19;285(5766):579-81. doi: 10.1038/285579a0.
3
Five TGA "stop" codons occur within the translated sequence of the yeast mitochondrial gene for cytochrome c oxidase subunit II.酵母线粒体细胞色素c氧化酶亚基II基因的翻译序列中存在五个TGA“终止”密码子。
Proc Natl Acad Sci U S A. 1979 Dec;76(12):6534-8. doi: 10.1073/pnas.76.12.6534.
4
A different genetic code in human mitochondria.人类线粒体中一种不同的遗传密码。
Nature. 1979 Nov 8;282(5735):189-94. doi: 10.1038/282189a0.
5
Directionally evolving genetic code: the UGA codon from stop to tryptophan in mitochondria.定向进化的遗传密码：线粒体中从终止密码子到色氨酸密码子的UGA密码子。
J Mol Evol. 1998 Oct;47(4):378-84. doi: 10.1007/pl00006395.
6
In vitro suppression of UGA codons in a mitochondrial mRNA.线粒体信使核糖核酸中UGA密码子的体外抑制
Nature. 1980 Sep 25;287(5780):361-3. doi: 10.1038/287361a0.
7
A deviant mitochondrial genetic code in prymnesiophytes (yellow-algae): UGA codon for tryptophan.定鞭藻门（黄藻）中一种异常的线粒体遗传密码：色氨酸的UGA密码子。
Curr Genet. 1997 Oct;32(4):296-9. doi: 10.1007/s002940050280.
8
Yeast mitochondrial tRNATrp injected with E. coli activating enzyme into Xenopus oocytes suppresses UGA termination.将酵母线粒体色氨酸转运核糖核酸与大肠杆菌活化酶一同注射到非洲爪蟾卵母细胞中，可抑制UGA终止作用。
Nature. 1981;293(5829):235-7. doi: 10.1038/293235a0.
9
Nucleotide sequence of the cox3 gene from Chondrus crispus: evidence that UGA encodes tryptophan and evolutionary implications.皱波角叉菜cox3基因的核苷酸序列：UGA编码色氨酸的证据及进化意义
Nucleic Acids Res. 1994 Apr 25;22(8):1400-3. doi: 10.1093/nar/22.8.1400.
10
UGA is read as tryptophan in Mycoplasma capricolum.在山羊支原体中，UGA被读作色氨酸。
Proc Natl Acad Sci U S A. 1985 Apr;82(8):2306-9. doi: 10.1073/pnas.82.8.2306.
引用本文的文献
1
Metatranscriptomic Sequencing of Sheath Blight-Associated Isolates of Revealed Multi-Infection by Diverse Groups of RNA Viruses.鞘腐病相关分离物的宏转录组测序揭示了不同 RNA 病毒群的多重感染。
Viruses. 2024 Jul 17;16(7):1152. doi: 10.3390/v16071152.
2
Allotopic expression of elucidates Atco-driven co-assembly of cytochrome oxidase and ATP synthase.异位表达阐明了 Atco 驱动细胞色素氧化酶和 ATP 合酶的共组装。
Life Sci Alliance. 2023 Aug 21;6(11). doi: 10.26508/lsa.202301965. Print 2023 Nov.
3
Dual Noncanonical Amino Acid Incorporation Enabling Chemoselective Protein Modification at Two Distinct Sites in Yeast.双非天然氨基酸掺入在酵母中两个不同位点实现化学选择性蛋白质修饰。
Biochemistry. 2023 Jul 18;62(14):2098-2114. doi: 10.1021/acs.biochem.2c00711. Epub 2023 Jun 28.
4
Genetic Code Expansion System for Tight Control of Gene Expression in Cell Lines.用于细胞系中基因表达严格控制的遗传密码扩展系统。
Insects. 2021 Dec 1;12(12):1081. doi: 10.3390/insects12121081.
5
Transfer RNAs: diversity in form and function.转移 RNA：形式与功能的多样性。
RNA Biol. 2021 Mar;18(3):316-339. doi: 10.1080/15476286.2020.1809197. Epub 2020 Sep 9.
6
Mitochondrial Genome (mtDNA) Mutations that Generate Reactive Oxygen Species.产生活性氧的线粒体基因组（mtDNA）突变
Antioxidants (Basel). 2019 Sep 11;8(9):392. doi: 10.3390/antiox8090392.
7
Tryptophan usage by Helicobacter pylori differs among strains.幽门螺杆菌对色氨酸的利用因菌株而异。
Sci Rep. 2019 Jan 29;9(1):873. doi: 10.1038/s41598-018-37263-6.
8
Genetic code flexibility in microorganisms: novel mechanisms and impact on physiology.微生物中的遗传密码灵活性：新机制及其对生理学的影响
Nat Rev Microbiol. 2015 Nov;13(11):707-721. doi: 10.1038/nrmicro3568. Epub 2015 Sep 22.
9
Ancient DNA sequence revealed by error-correcting codes.通过纠错码揭示的古代DNA序列。
Sci Rep. 2015 Jul 10;5:12051. doi: 10.1038/srep12051.
10
Recent developments of engineered translational machineries for the incorporation of non-canonical amino acids into polypeptides.用于将非天然氨基酸掺入多肽的工程化翻译机器的最新进展。
Int J Mol Sci. 2015 Mar 20;16(3):6513-31. doi: 10.3390/ijms16036513.
本文引用的文献
1
Mitochondrial genetics. IV. Allelism and mapping studies of oligomycin resistant mutants in S. cerevisiae.线粒体遗传学。IV. 酿酒酵母中寡霉素抗性突变体的等位性和图谱研究。
Mol Gen Genet. 1973 Sep 5;125(1):9-52. doi: 10.1007/BF00292982.
2
3
Studies on cytochrome c oxidase, IV[1--3]. Primary structure and function of subunit II.细胞色素c氧化酶研究，IV[1 - 3]。亚基II的一级结构与功能
Hoppe Seylers Z Physiol Chem. 1979 Apr;360(4):613-9.
4
Studies on cytochrome c oxidase, III. Relationship of cytochrome oxidase subunits to electron carriers of photophosphorylation.细胞色素c氧化酶研究，III. 细胞色素氧化酶亚基与光合磷酸化电子载体的关系。
Hoppe Seylers Z Physiol Chem. 1978 Aug;359(8):1011-3.
5
6
Nucleotide sequence of the mitochondrial structural gene for subunit 9 of yeast ATPase complex.酵母ATP酶复合体亚基9线粒体结构基因的核苷酸序列。
Proc Natl Acad Sci U S A. 1979 Apr;76(4):1663-7. doi: 10.1073/pnas.76.4.1663.
7
Assembly of the mitochondrial membrane system. The DNA sequence of a mitochondrial ATPase gene in Saccharomyces cerevisiae.线粒体膜系统的组装。酿酒酵母中线粒体ATP酶基因的DNA序列。
J Biol Chem. 1979 Jun 10;254(11):4617-23.
8
Localization on mitochondrial DNA of mutations leading to a loss of rutamycin-sensitive adenosine triphosphatase.导致鲁塔霉素敏感性三磷酸腺苷酶丧失的突变在线粒体DNA上的定位。
Eur J Biochem. 1976 Sep;68(1):113-9. doi: 10.1111/j.1432-1033.1976.tb10769.x.
9
Identification of two products of mitochondrial protein synthesis associated with mitochondrial adenosine triphosphatase from Neurospora crassa.鉴定与粗糙脉孢菌线粒体腺苷三磷酸酶相关的两种线粒体蛋白质合成产物。
Eur J Biochem. 1975 May;54(1):97-106. doi: 10.1111/j.1432-1033.1975.tb04118.x.
Zotero 插件