Sandhu Nicole P, Long Harry J, Johnson Kiley J, Degnim Amy C
Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
BMJ Case Rep. 2011 Mar 15;2011:bcr1220103590. doi: 10.1136/bcr.12.2010.3590.
A healthy 27-year-old woman presented to an outside institution with unilateral nipple pruritus and a slight brown discolouration. When her symptoms failed to respond to topical therapy, nipple biopsy revealed Paget's disease of the nipple. The patient sought further evaluation and care at our institution. Further investigation revealed multifocal breast cancer and the patient underwent bilateral mastectomies with sentinel lymph node biopsy followed by adjuvant systemic therapy. She is currently more than 4 years out from surgery and chemotherapy and has had no evidence of breast cancer recurrence.
一名27岁的健康女性因单侧乳头瘙痒和轻微褐色变色就诊于外院。局部治疗后症状无缓解，乳头活检显示为乳头派杰病。患者来我院寻求进一步评估和治疗。进一步检查发现多灶性乳腺癌，患者接受了双侧乳房切除术及前哨淋巴结活检，随后进行辅助全身治疗。目前，她已手术和化疗4年多，无乳腺癌复发迹象。
