Mannarini Laura, Morbini Patrizia, Bertino Giulia, Gatti Omar, Benazzo Marco
Department of Otorhinolaryngology, University of Pavia, IRCCS Policlinico S. Matteo Foundation, Pavia, Italy.
Case Rep Med. 2012;2012:616913. doi: 10.1155/2012/616913. Epub 2012 May 31.
Schwannoma is a neurogenic benign tumour arising from the proliferation of Schwann cells present in the peripheral nerve sheath of myelinated nerves. This proliferation can hypothetically appear in every anatomic region of the human body, but the nerve sheath tumors rarely occur within the larynx. In this paper the authors discuss the case of a 74-year-old female who presented to Emergency Unit (EU) for an important acute respiratory distress. Airway flexible endoscopy revealed a bulky mass of the aryepiglottic fold measuring 3.5 cm in diameter. The patient underwent tracheotomy and a single-step surgical excision treatment of the mass which was recognized as a schwannoma at pathological examination. Tracheotomy was closed 2 weeks postoperatively. After 18 months of followup, the patient is alive and free of disease and her voice had improved markedly.
施万细胞瘤是一种神经源性良性肿瘤，由存在于有髓神经外周神经鞘中的施万细胞增殖形成。理论上，这种增殖可出现在人体的每个解剖区域，但神经鞘瘤很少发生于喉部。本文作者讨论了一名74岁女性的病例，该患者因严重急性呼吸窘迫就诊于急诊科。气道可弯曲内镜检查发现杓会厌襞有一巨大肿物，直径3.5厘米。患者接受了气管切开术，并对肿物进行了一次性手术切除治疗，病理检查确诊为施万细胞瘤。术后2周气管切开伤口愈合。经过18个月的随访，患者存活且无疾病复发，声音也有明显改善。
