Keikotlhaile B M, Spanoghe P, Steurbaut W
Crop Protection Chemistry Laboratory, Department of Crop Protection Ghent University, Coupure Links 653, BE-Gent, Belgium.
Commun Agric Appl Biol Sci. 2011;76(4):853-61.
Pesticides are used in agriculture to improve food security by assuring good harvest, however, they can have harmful effects in human beings and animals. One of the harmful effects of pesticides is their carcinogenicity. Exposure to oncogenic compounds may result in cancer to the exposed animal or person. In this paper, exposure assessment of oncogenic potency of pesticides was performed from raw and processed fruits and vegetables. The oncogenic risk was calculated by multiplying the estimated daily intake (EDI) of the pesticide residue with the oncogenic potency factor (Q*) of the concerned pesticide. The total potential oncogenic risk was calculated to be 2.76 x 10(-3) before processing and 8.97 x 10(-4) after processing. The risk was higher than the EPA acceptable limit of 1 x10(-6). Despite the calculated levels exceeding the EPA acceptable limit, food processing activities reduced the dietary oncogenic risk to an average 33.8%.
农药在农业中被用于确保丰收以提高粮食安全，然而，它们可能对人类和动物产生有害影响。农药的有害影响之一是其致癌性。接触致癌化合物可能导致接触的动物或人患癌症。本文对生的和加工过的水果及蔬菜进行了农药致癌潜力的暴露评估。致癌风险是通过将农药残留的估计每日摄入量（EDI）与相关农药的致癌潜力因子（Q*）相乘来计算的。加工前计算出的总潜在致癌风险为2.76×10⁻³，加工后为8.97×10⁻⁴。该风险高于美国环境保护局（EPA）可接受的1×10⁻⁶的限值。尽管计算出的水平超过了EPA可接受的限值，但食品加工活动将饮食致癌风险平均降低了33.8%。
