Department of Biology and Genomics of Fruit Plants, FEM IASMA Research and Innovation Center, Foundation Edmund Mach di San Michele all'Adige, Trento, Italy.
Annu Rev Phytopathol. 2012;50:475-94. doi: 10.1146/annurev-phyto-081211-172931. Epub 2012 Jun 11.
The enterobacterial phytopathogen Erwinia amylovora causes fire blight, an invasive disease that threatens a wide range of commercial and ornamental Rosaceae host plants. The response elicited by E. amylovora in its host during disease development is similar to the hypersensitive reaction that typically leads to resistance in an incompatible host-pathogen interaction, yet no gene-for-gene resistance has been described for this host-pathogen system. Comparative genomic analysis has found an unprecedented degree of genetic uniformity among strains of E. amylovora, suggesting that the pathogen has undergone a recent genetic bottleneck. The genome of apple, an important host of E. amylovora, has been sequenced, creating new opportunities for the study of interactions between host and pathogen during fire blight development and for the identification of resistance genes. This review includes recent advances in the genomics of both host and pathogen.
肠杆菌植物病原菌梨火疫病菌（Erwinia amylovora）引发火疫病，这是一种侵袭性疾病，威胁着广泛的商业和观赏蔷薇科寄主植物。在疾病发展过程中，E. amylovora 在其寄主中引发的反应与通常导致不亲和的寄主-病原体相互作用中产生抗性的过敏反应相似，但尚未为该寄主-病原体系统描述基因对基因抗性。比较基因组分析发现，E. amylovora 菌株之间存在前所未有的遗传均匀性，表明该病原体经历了最近的遗传瓶颈。苹果的基因组已被测序，苹果是 E. amylovora 的重要寄主，这为研究火疫病发展过程中寄主与病原体之间的相互作用以及鉴定抗性基因创造了新的机会。本综述包括了宿主和病原体基因组学的最新进展。
