Gaillard J M
Sleep. 1978 Winter;1(2):133-47. doi: 10.1093/sleep/1.2.133.
This study was designed to compare the sleep of a carefully selected group of patients with chronic primary insomnia toage- and sex-matched controls, in order to investigate the possible physiopathological role of slow wave sleep deficiency in this disturbance. In addition, the effect of age on normal sleep was studied in a group of 40 normal subjects. Sleep was recorded in the laboratory and automatically scored with an electronic system already described. The general trends of sleep stages were computed. Aging in normal subjects was characterized by a sharp decrease of stage 4, but a good stability of stage 3. Insomniacs' sleep showed a sleep-waking imbalance and a marked deficiency in stages 3 and 4. This deficiency seems to be similar to the age effect in normals, but more accentuated; it cannot be attributed merely to increased pressure of wakefulness. We suggest that slow wave sleep is involved in sleep induction and maintenance, and that its deficiency is linked to the fragility of sleep in chronic primary insomnia.
本研究旨在比较精心挑选的一组慢性原发性失眠患者与年龄和性别匹配的对照组的睡眠情况，以调查慢波睡眠不足在这种紊乱中可能的生理病理作用。此外，在一组40名正常受试者中研究了年龄对正常睡眠的影响。在实验室记录睡眠，并使用已描述的电子系统自动评分。计算睡眠阶段的总体趋势。正常受试者的衰老特征是4期急剧减少，但3期保持良好稳定。失眠患者的睡眠表现出睡眠-觉醒失衡以及3期和4期明显不足。这种不足似乎与正常人的年龄效应相似，但更为明显；它不能仅仅归因于觉醒压力的增加。我们认为慢波睡眠参与睡眠诱导和维持，其不足与慢性原发性失眠中睡眠的脆弱性有关。
