Pascual J M, Górriz J L, Prosper M, Collado A, Belda A, Michavila J, Redón J
Servicio de Medicina Interna, Hospital de Sagunto, Valencia.
Rev Clin Esp. 1990 Jun;187(1):6-9.
Fourty four patients suffering non traumatic rhabdomyolysis (RM) are studied. The most frequently encountered etiologies were neurologic abnormalities in 26 patients, followed by infections in 7 patients and metabolic abnormalities in four cases. Eleven patients (25%) presented several associated factors. The clinical manifestations of RM were not very significant, with only 18% of patients presenting muscle pain, 38.6% proteinuria and 36.4% hematuria. A significant increase in K, CPK, LDH, and ASAT values was observed after the RM episode (p less than 0.05). Those patients with an infectious RM were older (p less than 0.05) and presented higher urea (p less than 0.01) and creatinine (p less than 0.05) values. Only two patients presented renal failure. One patient with septic shock died. RM is a relatively common condition, often secondary to multiple systemic processes, which can go unnoticed due to the underlying disease.
对44例非创伤性横纹肌溶解症(RM)患者进行了研究。最常见的病因是26例患者出现神经功能异常,其次是7例患者感染,4例患者出现代谢异常。11例患者(25%)存在多种相关因素。RM的临床表现不太明显,只有18%的患者出现肌肉疼痛,38.6%出现蛋白尿,36.4%出现血尿。RM发作后,血钾、肌酸磷酸激酶(CPK)、乳酸脱氢酶(LDH)和谷草转氨酶(ASAT)值显著升高(p<0.05)。感染性RM患者年龄较大(p<0.05),尿素(p<0.01)和肌酐(p<0.05)值较高。只有2例患者出现肾衰竭。1例感染性休克患者死亡。RM是一种相对常见的疾病,通常继发于多种全身性疾病过程,由于基础疾病可能未被注意到。