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头痛专项的多学科交叉治疗方案的结果。

Outcomes of a headache-specific cross-sectional multidisciplinary treatment program.

机构信息

Headache Center Berlin, Sankt Gertrauden Krankenhaus Berlin, Germany.

出版信息

Headache. 2012 Jul-Aug;52(7):1094-105. doi: 10.1111/j.1526-4610.2012.02189.x. Epub 2012 Jun 15.

Abstract

AIM

Chronic headache is a disabling disorder that is frequently poorly managed in general clinical practice.

OBJECTIVES

To investigate primary (headache frequency in days/month) and secondary (headache-related disability, lost work/school time, anxiety and depression, amount and intake frequency of acute medication) 12-month outcomes of a headache-specific cross-sectional outpatient and inpatient multidisciplinary treatment program using a dedicated computer system for data collection and corresponding between integrated care team in a tertiary headache center and practicing headache specialists.

BACKGROUND

A need for integrated headache care using comprehensive and standardized assessment for diagnosis of headache, psychiatric comorbidity, and burden of disease exists. There are little published data on long-term efficacy of multidisciplinary treatment programs for chronic headache.

DESIGN

A prospective, observational, 12-month, follow-up study.

SUBJECTS AND METHODS

Prospectively recruited consecutive patients with frequent difficult-to-treat headaches (n = 201; 63 migraine, 11 tension-type headache, 59 combined migraine/tension-type headache, and 68 medication overuse headache) were enrolled. Outcome measures included prospective headache diaries, a medication survey, Migraine Disability Assessment, 12-item short form health survey, and the Hospital Anxiety and Depression Scale.

RESULTS

The primary outcome of a reduction of ≥50% of headache frequency (days/month) was observed in 62.7%. Mean headache frequency decreased from 14.4 ± 8.2 to 7.6 ± 8.3 days/month, P < .0001. Secondary outcomes improved significantly in the total cohort and all headache subgroups. Predictors for good outcome were younger age, few days lost at work/school, and familiarity with progressive muscle relaxation therapy at baseline.

CONCLUSIONS

The present analysis provided support for a cross-sectional multidisciplinary integrated headache-care program.

摘要

目的

慢性头痛是一种常见的致残性疾病,但在常规临床实践中常常管理不善。

目标

采用专门的计算机系统收集数据,对头痛专科门诊和住院多学科综合治疗项目的主要(每月头痛天数)和次要(头痛相关残疾、旷工/缺课时间、焦虑和抑郁、急性药物使用量和使用频率)12 个月结果进行调查,该项目整合了三级头痛中心的护理团队和头痛专科医生的工作。

背景

需要采用综合性和标准化评估来整合头痛护理,以诊断头痛、精神共病和疾病负担。关于慢性头痛多学科治疗方案长期疗效的数据很少。

设计

前瞻性、观察性、12 个月随访研究。

对象和方法

连续纳入 201 例(63 例偏头痛、11 例紧张型头痛、59 例偏头痛和紧张型头痛混合性头痛、68 例药物过度使用性头痛)频繁发作且难以治疗的头痛患者。主要结局指标包括前瞻性头痛日记、药物使用调查、偏头痛残疾评估量表、12 项简明健康调查和医院焦虑抑郁量表。

结果

62.7%的患者头痛频率(每月天数)降低≥50%。头痛频率从 14.4±8.2 天/月降至 7.6±8.3 天/月,差异具有统计学意义(P<0.0001)。所有头痛亚组和总体队列的次要结局均显著改善。良好结局的预测因素包括年龄较小、工作/上学缺勤天数较少以及基线时熟悉渐进性肌肉松弛疗法。

结论

本分析为多学科综合头痛护理项目提供了支持。

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