Miyazawa Tomonori, Ebe Kazuyu, Fujita Nobuhiro, Koide Norihiko, Honma Kenji, Ikarashi Toshihiko
Dept. of Surgery, Joetsu General Hospital.
Gan To Kagaku Ryoho. 2012 Jun;39(6):1001-3.
A 70-year-old man was admitted to our hospital for constipation. A clinical examination showed locally advanced rectal cancer with possible invasion to the prostate gland and pelvic wall. After performing colostomy, he underwent neoadjuvant radiation therapy (40 Gy) and six courses of a XELOX and bevacizumab regimen. A subsequent examination demonstrated significant reduction of the tumor, so we performed super low anterior resection and colo-anal anastomosis. Pathological examination revealed no residual cancer cells and showed pathological CR. Neoadjuvant chemoradiotherapy with XELOX and bevacizumab were useful for down staging and function-preserving surgery in patients with locally advanced rectal cancer.
一名70岁男性因便秘入住我院。临床检查显示为局部晚期直肠癌，可能侵犯前列腺和盆腔壁。行结肠造口术后，他接受了新辅助放疗（40 Gy）以及六个疗程的XELOX和贝伐单抗方案治疗。随后的检查显示肿瘤明显缩小，因此我们进行了超低位前切除术和结肠肛管吻合术。病理检查未发现残留癌细胞，显示为病理完全缓解。XELOX和贝伐单抗新辅助放化疗对局部晚期直肠癌患者降期及保留功能手术有效。
