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[1例经新辅助卡培他滨、奥沙利铂、贝伐单抗及放疗成功治疗的局部浸润性直肠癌切除病例]

[A resected case of locally invasive rectal cancer successfully treated with neoadjuvant capecitabine, oxaliplatin, bevacizumab and radiation therapy].

作者信息

Suzuki Shunji, Shigaki Nobuyuki, Yokoyama Sachio, Yamashita Hiroya, Sugita Hiroki, Arima Nobuyuki

机构信息

Dept. of Surgery, Kumamoto Municipal Hospital.

出版信息

Gan To Kagaku Ryoho. 2011 Sep;38(9):1545-7.

Abstract

A 57-year-old man was admitted to our hospital with a complaint of perineal pain. He was diagnosed as advanced rectal cancer with an invasion of prostate, and we conducted neoadjuvant capecitabine, oxaliplatin, bevacizumab and radiation therapy. After chemoradiation therapy, the tumor regressed to an ulcerative lesion without invasion of the prostate. Abdominoperineal resection was then performed without radical resection. The tumor regressed to an ulcer and only a few cancer cells were detected in the submucosal layer pathologically.

摘要

一名57岁男性因会阴部疼痛入院。他被诊断为晚期直肠癌伴前列腺侵犯,我们对其进行了新辅助卡培他滨、奥沙利铂、贝伐单抗和放射治疗。放化疗后,肿瘤退缩为溃疡性病变,无前列腺侵犯。随后进行了腹会阴切除术,但未进行根治性切除。肿瘤退缩为溃疡,病理检查在黏膜下层仅检测到少数癌细胞。

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