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两只隐睾犬中与女性化综合征及精索扭转相关的支持细胞瘤。

Sertoli cell tumors associated with feminizing syndrome and spermatic cord torsion in two cryptorchid dogs.

作者信息

Quartuccio Marco, Marino Gabriele, Garufi Giuseppe, Cristarella Santo, Zanghì Antonina

机构信息

Department of Veterinary Public Health, University of Messina 98168 Messina, Italy.

出版信息

J Vet Sci. 2012 Jun;13(2):207-9. doi: 10.4142/jvs.2012.13.2.207.

DOI:10.4142/jvs.2012.13.2.207
PMID:22705745
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3386348/
Abstract

The association of cryptorchidism, functional Sertoli cell tumors, and spermatic cord torsion has been rarely reported in the literature. Two dogs were admitted for bilateral skin alopecia and weight loss. Both animals were cryptorchid and displayed a pendulous preputial sheath, prostate hypertrophy, and increased levels of circulating oestrogen. Transabdominal palpation and ultrasonography revealed the presence of neoplastic retained gonads. During surgery, spermatic cord torsion was also detected in the enlarged neoplastic testes of both dogs. Histologic examination confirmed the presence of Sertoli cell tumors that were primarily responsible for the feminizing syndrome. Complete remission of all symptoms occurred within 3 months after orchiectomy.

摘要

隐睾症、功能性支持细胞瘤和精索扭转之间的关联在文献中鲜有报道。两只犬因双侧皮肤脱毛和体重减轻入院。两只动物均为隐睾,表现为包皮鞘下垂、前列腺肥大以及循环雌激素水平升高。经腹触诊和超声检查发现存在肿瘤性残留性腺。手术过程中,在两只犬增大的肿瘤性睾丸中也检测到精索扭转。组织学检查证实存在主要导致雌性化综合征的支持细胞瘤。睾丸切除术后3个月内所有症状完全缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d5c/3386348/dda65ad1703b/jvs-13-207-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d5c/3386348/e99fe0ea7a98/jvs-13-207-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d5c/3386348/8649426092ac/jvs-13-207-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d5c/3386348/dda65ad1703b/jvs-13-207-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d5c/3386348/e99fe0ea7a98/jvs-13-207-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d5c/3386348/8649426092ac/jvs-13-207-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d5c/3386348/dda65ad1703b/jvs-13-207-g003.jpg

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本文引用的文献

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Oestrogen-induced bone marrow aplasia in a dog with a Sertoli cell tumour.一只患有支持细胞瘤的犬雌激素诱导的骨髓再生障碍
J Small Anim Pract. 2002 Aug;43(8):365-9. doi: 10.1111/j.1748-5827.2002.tb00087.x.
2
Prostatic adenocarcinoma with concurrent Sertoli cell tumor in a dog.一只患有前列腺腺癌并发支持细胞瘤的犬
Can Vet J. 1981 Jul;22(7):230-3.
3
Spermatic cord torsion and Sertoli cell tumor in a dog.一只犬的精索扭转和支持细胞瘤
犬隐秘型睾丸中的支持细胞瘤伴前列腺鳞状化生导致犬的链球菌性前列腺炎和心内膜炎合并血栓栓塞
Vet Res Commun. 2023 Sep;47(3):1759-1766. doi: 10.1007/s11259-022-10065-y. Epub 2023 Jan 31.
4
Case Report: Disorder of Sexual Development in a Chinese Crested Dog With XX/XY Leukocyte Chimerism and Mixed Cell Testicular Tumors.病例报告:一只患有XX/XY白细胞嵌合体和混合细胞性睾丸肿瘤的中国冠毛犬的性发育障碍
Front Vet Sci. 2022 Jul 8;9:937991. doi: 10.3389/fvets.2022.937991. eCollection 2022.
5
The Case of Atypical Sexual Attractiveness in a Male Domestic Dog-A Case Study.一只雄性家犬的非典型性性吸引力案例——一项案例研究
Animals (Basel). 2021 Nov 4;11(11):3156. doi: 10.3390/ani11113156.
6
Management of an invasive and metastatic Sertoli cell tumor with associated myelotoxicosis in a dog.一只患有侵袭性转移性支持细胞瘤并伴有骨髓毒性的犬的治疗
Can Vet J. 2016 Mar;57(3):299-304.
7
Unilateral cryptorchidism induces morphological changes of testes and hyperplasia of Sertoli cells in a dog.单侧隐睾症会导致犬睾丸形态改变和支持细胞增生。
Lab Anim Res. 2014 Dec;30(4):185-9. doi: 10.5625/lar.2014.30.4.185. Epub 2014 Dec 24.
J Am Vet Med Assoc. 1983 Oct 15;183(8):879-81.
4
The relationship between cryptorchidism and canine testicular neoplasia.隐睾症与犬睾丸肿瘤之间的关系。
J Am Vet Med Assoc. 1969 Dec 15;155(12):2005-10.
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