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一只患有支持细胞瘤的犬雌激素诱导的骨髓再生障碍

Oestrogen-induced bone marrow aplasia in a dog with a Sertoli cell tumour.

作者信息

Sanpera N, Masot N, Janer M, Romeo C, de Pedro R

机构信息

Hospital Veterinari Via Aurèlia, Barcelona, Spain.

出版信息

J Small Anim Pract. 2002 Aug;43(8):365-9. doi: 10.1111/j.1748-5827.2002.tb00087.x.

DOI:10.1111/j.1748-5827.2002.tb00087.x
PMID:12201446
Abstract

A 10-year-old male Drahthaar dog with unilateral cryptorchidism was examined because of feminisation and myelotoxicity. Radiography and ultrasonography revealed an abdominal mass which was surgically removed. The mass was identified as a Sertoli cell tumour on histological examination. Findings on bone marrow examination were compatible with aplasia due to the oestrogens secreted by the tumoral cells. Treatment with fluids, antibiotics, whole blood transfusions, corticosteroids and lithium carbonate was unsuccessful. Survival time was 22 days after surgery.

摘要

一只10岁的雄性德国刚毛指示犬因出现雌性化和骨髓毒性而接受检查,该犬患有单侧隐睾症。放射学和超声检查发现腹部有一肿块,遂通过手术将其切除。组织学检查显示该肿块为支持细胞瘤。骨髓检查结果与肿瘤细胞分泌的雌激素导致的发育不全相符。给予补液、抗生素、全血输血、皮质类固醇和碳酸锂治疗均未成功。术后存活时间为22天。

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