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患者髂骨自体骨移植后发生白色念珠菌性髂骨骨髓炎:病例报告及文献复习。

Iliac bone Candida albicans osteomyelitis in a patient with iliac crest bone autograft: a case report and review of the literature.

机构信息

Division of Infectious Diseases, Clinica Universidad de Navarra, Pamplona, Spain.

出版信息

Infection. 2012 Aug;40(4):445-9. doi: 10.1007/s15010-012-0276-z. Epub 2012 Jun 16.

DOI:10.1007/s15010-012-0276-z
PMID:22706637
Abstract

Candida osteomyelitis is a well recognized but infrequent entity. We describe an interesting case of iliac bone C. albicans osteomyelitis as a result of a surgical trauma of an iliac bone for the auto-grafting of a fracture in the lumbar spine. The peri-operative acquisition of Candida was by the inoculation of a yeast colonizing the skin. Remarkably, several risk factors described for Candida infection and candidemia were absent. The patient also presented with a local fistula. The iliac crest was the only bone affected and local pain was the only symptom present in our case. Diagnosis was made by multiple-specimen biopsy obtained by surgery. Treatment with fluconazole was successful.

摘要

白色念珠菌性骨髓炎是一种公认但罕见的疾病。我们描述了一例有趣的病例,即由于腰椎骨折的自体移植手术而导致的髂骨白色念珠菌性骨髓炎。念珠菌是通过定植在皮肤上的酵母接种而在围手术期获得的。值得注意的是,缺失了许多描述的念珠菌感染和念珠菌血症的危险因素。该患者还出现了局部瘘管。受影响的唯一骨骼是髂嵴,我们的病例中仅出现局部疼痛这一症状。通过手术获得的多部位活检进行诊断。氟康唑治疗取得了成功。

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Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America.念珠菌病管理临床实践指南:美国传染病学会2009年更新版
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Infection. 2014 Jun;42(3):503-10. doi: 10.1007/s15010-013-0582-0. Epub 2014 Jan 21.
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Clin Infect Dis. 2001 Aug 15;33(4):523-30. doi: 10.1086/322634. Epub 2001 Jul 20.
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