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内镜下第三脑室造瘘术成功评分(ETVSS)对50例儿科患者系列手术成功情况的预测。我们患者的手术结果可预测吗?

Endoscopic Third Ventriculostomy Success Score (ETVSS) predicting success in a series of 50 pediatric patients. Are the outcomes of our patients predictable?

作者信息

García Laura González, López Bienvenido Ros, Botella Guillermo Ibáñez, Páez Miguel Domínguez, da Rosa Sandra Pérez, Rius Francisca, Sánchez Miguel Angel Arráez

机构信息

Department of Neurosurgery, HRU Carlos Haya, Avenida Carlos Haya s/n, 29010 Málaga, Spain.

出版信息

Childs Nerv Syst. 2012 Aug;28(8):1157-62. doi: 10.1007/s00381-012-1836-3. Epub 2012 Jun 17.

DOI:10.1007/s00381-012-1836-3
PMID:22706984
Abstract

PURPOSE

In our series of endoscopic third ventriculostomy (ETV), we sought to establish the relationship between the preoperative prediction using the Endoscopic Third Ventriculostomy Success Score (ETVSS) and the postsurgical success rate.

MATERIALS AND METHODS

This descriptive analytical study comprised 50 pediatric patients who underwent 58 ETV procedures between 2003 and 2011. Data regarding clinical, surgical, and radiological findings were obtained from a continuously updated database. For each patient, we calculated the ETVSS, based on the patient's age, hydrocephalus etiology, and presence of a previous shunt. We considered success to be an established or improved clinical state and at least one of the following radiological criteria: (a) reduction in ventricular size or stable ventricles with disappearance of periventricular edema and increased subarachnoid space over cerebral convexities, (b) flow artifact in sagittal T2FSE MR, or (c) bidirectional flow signal in 2D-CPC MR. Statistical significance was set at p < 0.05. Six months was the minimum postoperative follow-up required.

RESULTS

The ETV was successful in 29 patients (58 %). Patients aged over 1 year achieved the best results (p < 0.019). For those who underwent successful ETV, the mean ETVSS was 71.03 (95 % CI, 66.23-75.84). In those for whom the ETV was not successful, the mean ETVSS was 60 (95 % CI, 53.09-66.90); (p < 0.007).

CONCLUSIONS

The success of ETV in our series could have been predicted by ETVSS. Predictability could help establish stricter surgical selection criteria, thereby obtaining higher success rates, as well as preparing the patients and their families for expected outcomes.

摘要

目的

在我们的内镜下第三脑室造瘘术(ETV)系列研究中,我们试图确定使用内镜下第三脑室造瘘术成功评分(ETVSS)进行术前预测与术后成功率之间的关系。

材料与方法

这项描述性分析研究纳入了2003年至2011年间接受58例ETV手术的50例儿科患者。有关临床、手术和放射学检查结果的数据来自一个持续更新的数据库。对于每位患者,我们根据其年龄、脑积水病因和既往是否有分流装置来计算ETVSS。我们将成功定义为临床状态稳定或改善,且至少符合以下放射学标准之一:(a)脑室大小缩小或脑室稳定,脑室周围水肿消失,脑凸面蛛网膜下腔增宽;(b)矢状位T2FSE MR上的血流伪影;或(c)二维相位对比造影(2D-CPC)MR上的双向血流信号。统计学显著性设定为p < 0.05。术后随访时间最短为6个月。

结果

29例患者(58%)的ETV手术成功。1岁以上的患者取得了最佳效果(p < 0.019)。对于ETV手术成功的患者,平均ETVSS为71.03(95%可信区间,66.23 - 75.84)。对于ETV手术不成功的患者,平均ETVSS为60(95%可信区间,53.09 - 66.90);(p < 0.007)。

结论

在我们的系列研究中,ETV的成功可以通过ETVSS进行预测。预测性有助于建立更严格的手术选择标准,从而获得更高的成功率,并让患者及其家属对预期结果做好准备。

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Evaluating the Children's Hospital of Alabama endoscopic third ventriculostomy experience using the Endoscopic Third Ventriculostomy Success Score: an external validation study.使用内镜下第三脑室造瘘术成功评分评估阿拉巴马州儿童医院的内镜下第三脑室造瘘术经验:一项外部验证研究。
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Use of the ETV Success Score to explain the variation in reported endoscopic third ventriculostomy success rates among published case series of childhood hydrocephalus.使用ETV成功评分来解释已发表的儿童脑积水病例系列中所报道的内镜下第三脑室造瘘术成功率的差异。
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Predicting who will benefit from endoscopic third ventriculostomy compared with shunt insertion in childhood hydrocephalus using the ETV Success Score.使用ETV成功评分预测在儿童脑积水患者中,与分流术相比,哪些患者将从内镜下第三脑室造瘘术中获益。
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Endoscopic third ventriculostomy in the treatment of childhood hydrocephalus.内镜下第三脑室造瘘术治疗儿童脑积水
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