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6个月以下儿童梗阻性脑积水的内镜下第三脑室造瘘术。

Endoscopic third ventriculostomy for obstructive hydrocephalus in children younger than 6 months of age.

作者信息

Ogiwara Hideki, Dipatri Arthur J, Alden Tord D, Bowman Robin M, Tomita Tadanori

机构信息

Division of Neurosurgery, Children's Memorial Hospital, Chicago, IL, USA.

出版信息

Childs Nerv Syst. 2010 Mar;26(3):343-7. doi: 10.1007/s00381-009-1019-z.

DOI:10.1007/s00381-009-1019-z
PMID:19915853
Abstract

PURPOSE

The outcome of endoscopic third ventriculostomy (ETV) is worse in children younger than 2 years old and especially in infants, and controversies still exist whether ETV might be superior to shunt placement in this age group. We retrospectively analyzed the data of 23 patients younger than 6 months of age treated with ETV and assessed its feasibility as a first choice of treatment for hydrocephalus.

METHODS

Between 1994 and 2008 in our clinic, 23 patients younger than 6 months having presented with obstructive hydrocephalus were treated endoscopically. The etiology of hydrocephalus was congenital aqueduct stenosis in 11 patients, posthemorrhagic obstruction in six patients, myelomeningocele in two patients, postmeningitis in two patients, Chiari I malformation in one patients, and Dandy walker variant in one patient. ETV was considered successful when no shunt operation was needed in the patient.

RESULTS

ETV was successful in eight patients with regression of intracranial hypertension. In the remaining 15 patients, ventriculoperitoneal shunt implantation was necessary. Total success rate in our group of patients was 34.8%. In patients younger than 3 months of age (n=12), success rate was 25.0%. In patients from 3 to 6 months of age (n=11), success rate was 45.5%. Complication included intraventricular hemorrhage in one patient, meningitis and cerebrospinal fluid leak in one patient, and meningitis in one patient.

CONCLUSIONS

Based on our experience, ETV could be the first method of choice for hydrocephalus in children younger than 6 months of age, especially in patients older than 3 months of age.

摘要

目的

内镜下第三脑室造瘘术(ETV)在2岁以下儿童尤其是婴儿中的治疗效果较差,对于该年龄组ETV是否优于分流术仍存在争议。我们回顾性分析了23例6个月以下接受ETV治疗的患者的数据,并评估了其作为脑积水首选治疗方法的可行性。

方法

1994年至2008年期间,我们诊所对23例6个月以下出现梗阻性脑积水的患者进行了内镜治疗。脑积水的病因包括:11例先天性导水管狭窄、6例出血后梗阻、2例脊髓脊膜膨出、2例脑膜炎后、1例Chiari I畸形和1例Dandy walker变异型。若患者无需进行分流手术,则认为ETV治疗成功。

结果

8例患者ETV治疗成功,颅内高压消退。其余15例患者需要进行脑室腹腔分流术植入。我们这组患者的总成功率为34.8%。3个月以下患者(n = 12)的成功率为25.0%。3至6个月患者(n = 11)的成功率为45.5%。并发症包括1例脑室内出血、1例脑膜炎和脑脊液漏、1例脑膜炎。

结论

根据我们的经验,ETV可以作为6个月以下儿童脑积水的首选治疗方法,尤其是3个月以上的患者。

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