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一种套管针引导的补片套件修复外侧缺损的临床疗效

Clinical efficacy of a trocar-guided mesh kit for repairing lateral defects.

作者信息

Ek Marion, Altman Daniel, Gunnarsson Jonas, Falconer Christian, Tegerstedt Gunilla

机构信息

Division of Obstetrics and Gynaecology, Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.

出版信息

Int Urogynecol J. 2013 Feb;24(2):249-54. doi: 10.1007/s00192-012-1833-9. Epub 2012 Jun 16.

Abstract

INTRODUCTION AND HYPOTHESIS

The optimal surgery for lateral defects is not well defined. Our objective was to assess the effects of anterior trocar-guided transvaginal mesh repair versus anterior colporrhaphy in women with lateral defects.

METHODS

This subanalysis from a randomized controlled trial of mesh kit versus anterior colporrhaphy assessed 99 patient diagnosed at baseline with lateral defects in the anterior vaginal wall. Thirty-nine patients underwent anterior colporrhaphy and 60 anterior trocar-guided transvaginal mesh surgery.

RESULTS

One year after surgery, a persistent lateral defect was significantly more common after colporrhaphy compared with transvaginal mesh [11/32 (34.4 %) vs 1/42 (2.4 %), risk ratio (RR) 14.4, 95 % confidence interval (CI) 2.0-106.1; P < 0.001)] However, there were no significant differences between treatment groups with regard to subjective symptoms as reflected by the overall Urogenital Distress Inventory scores, with mean difference from baseline 37.3 ± 50.6 in the colporrhaphy group vs 39.0 ± 45.8 in the mesh group (p = 0.61).

CONCLUSIONS

Use of a transvaginal mesh kit increases the odds for anatomical correction of lateral defects compared with anterior colporrhaphy but does not necessarily improve lower urinary tract symptoms.

摘要

引言与假设

外侧缺损的最佳手术方式尚无明确定义。我们的目的是评估前套管针引导下经阴道网片修补术与前盆腔修补术对有外侧缺损女性的影响。

方法

这项来自网片套件与前盆腔修补术随机对照试验的亚分析,评估了99例基线诊断为阴道前壁外侧缺损的患者。39例患者接受了前盆腔修补术,60例接受了前套管针引导下经阴道网片修补术。

结果

术后一年,与经阴道网片修补术相比,前盆腔修补术后持续性外侧缺损更为常见[11/32(34.4%)对1/42(2.4%),风险比(RR)14.4,95%置信区间(CI)2.0 - 106.1;P < 0.001]。然而,根据泌尿生殖系统困扰量表总分反映的主观症状,治疗组之间无显著差异,前盆腔修补术组与基线相比平均差异为37.3 ± 50.6,网片修补术组为39.0 ± 45.8(p = 0.61)。

结论

与前盆腔修补术相比,使用经阴道网片套件增加了解剖学上纠正外侧缺损的几率,但不一定能改善下尿路症状。

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