人乳头瘤病毒：鉴别新发原发性肺癌与既往头颈部鳞状细胞癌转移所致疾病。
Human papilloma virus: differentiating new primary lung cancer versus metastatic disease from previous head and neck squamous cell carcinoma.
作者信息
Giuliani Meredith E, Weinreb Ilan, Hope Andrew J
机构信息
Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario, Canada.
出版信息
BMJ Case Rep. 2011 Feb 24;2011:bcr0920103377. doi: 10.1136/bcr.09.2010.3377.
Abstract
Distinguishing new primary lung tumours from lung metastasis in patients with head and neck squamous cell carcinoma (SCC) is a challenging clinical problem. Histological examination is not always able to distinguish between these scenarios as SCC is common in both sites. Here the authors present a case of metachronous cancers of the head and neck and lung in which human papilloma virus testing was proposed as a mechanism to distinguish primary from metastatic carcinoma.
摘要
区分头颈部鳞状细胞癌（SCC）患者的新发原发性肺肿瘤与肺转移瘤是一个具有挑战性的临床问题。由于SCC在这两个部位都很常见，组织学检查并不总能区分这些情况。在此，作者报告了一例头颈部和肺部异时性癌的病例，其中提出进行人乳头瘤病毒检测，作为区分原发性癌和转移性癌的一种方法。
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