用于青少年和成人的无细胞百日咳疫苗的免疫原性和反应原性
[Immunogenicity and reactogenicity of acellular pertussis vaccines intended for adolescent and adults].
作者信息
Zawadka Monika, Lutyńska Anna
机构信息
Zakład Badania Surowic i Szczepionek Narodowego Instytutu Zdrowia Publicznego--Państwowego Zakładu Higieny w Warszawie.
出版信息
Przegl Epidemiol. 2012;66(1):99-105.
Although high immunization status against pertussis maintained in neonates and children, the increase in pertussis cases has been observed in Poland since 1990-ies, especially in adolescent and adults. Wide use of pertussis acellular vaccines intended for adolescents and adult's immunization might prolong immunity against pertussis. The goal of the work was to present current view of immunogenicity and reactogenicity of those pertussis vaccines in different age groups.
尽管新生儿和儿童对百日咳保持着较高的免疫状态，但自20世纪90年代以来，波兰的百日咳病例有所增加，尤其是在青少年和成年人中。广泛使用用于青少年和成人免疫的无细胞百日咳疫苗可能会延长对百日咳的免疫力。这项工作的目的是介绍这些百日咳疫苗在不同年龄组中的免疫原性和反应原性的当前观点。
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