Chichinadze K, Tkemaladze D, Lazarashvili A
Adv Gerontol. 2012;25(1):23-8.
The recent discovery of a new class of RNA in a centrosome may be an indirect evidence of the centrosomal hypothesis of cellular ageing and differentiation. The presence of a reverse transcriptase domain in this class of RNA, together with its specificity to this organelle, makes the centrosome a place of information memorizing and reproduction. This feature of centrosome is one of the main points of centrosomal hypothesis of cell aging and differentiation.
最近在中心体中发现的一类新RNA可能是细胞衰老和分化的中心体假说的间接证据。这类RNA中存在逆转录酶结构域,以及其对该细胞器的特异性,使得中心体成为信息存储和复制的场所。中心体的这一特性是细胞衰老和分化的中心体假说的主要观点之一。