Shatilo V B, Bondarenko E V, Antoniuk-Shcheglova I A
Adv Gerontol. 2012;25(1):84-9.
The incidence of dysmetabolic factors in 100 elderly patients with hypertension stage II and the role of melatoninproducing function of epiphysis (pineal gland) in the development of these disorders were studied. It was found that the decrease of melatoninproducing function is one of the factors causing disorders of carbohydrate and lipid metabolism in elderly patients with hypertension. Simultaneous application of Melatonin with lisinopril or amlodipine have the normalizing effect on metabolic parameters affected in patients with arterial hypertension.
对100例老年II期高血压患者代谢紊乱因素的发生率以及松果体褪黑素分泌功能在这些疾病发展中的作用进行了研究。发现褪黑素分泌功能下降是老年高血压患者碳水化合物和脂质代谢紊乱的因素之一。褪黑素与赖诺普利或氨氯地平联合应用对动脉高血压患者受影响的代谢参数有正常化作用。
