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心内科医生治疗高血压的性别差异:PARITE 研究。

Gender-related differences in the management of hypertension by cardiologists: the PARITE study.

机构信息

Pôle cardiovasculaire et pulmonaire, médecine vasculaire et hypertension artérielle, faculté Henri-Warembourg, université de Lille, CHRU de Lille, France.

出版信息

Arch Cardiovasc Dis. 2012 May;105(5):271-80. doi: 10.1016/j.acvd.2012.03.003. Epub 2012 May 23.

Abstract

BACKGROUND

Several studies have shown gender differences in the management of cardiovascular risk factors and diseases. Whether the management of hypertension by cardiologists in France differs according to patient gender has not been fully investigated.

AIMS

The main objective of this cross-sectional, multicentre study was to examine the management according to gender of hypertensive patients by office-based cardiologists in France.

METHODS

Cardiologists were asked to include consecutively two men and two women attending a routine consultation for essential hypertension. Therapeutic management was evaluated by comparing cardiovascular investigations in the preceding 6 months and hypertension control according to gender and the patients' global cardiovascular risk.

RESULTS

Overall, data from 3440 adult patients (53% men) referred to 654 cardiologists were analysed. Hypertension was uncontrolled in 76% of both men and women and 69% were at high global cardiovascular risk (75% of men, 62% of women; P<0.001). Significantly fewer cardiovascular investigations had been performed in the preceding 6 months in women (22.6% vs 44.2% in men; P<0.001). The treatment regimen was changed by the cardiologist in approximately 50% of patients regardless of gender or global cardiovascular risk.

CONCLUSIONS

The PARITE study shows that in French office-based cardiology practice, the antihypertensive regimen is adjusted as often in female as in male patients. However, the results suggest that there is room for improvement in the investigation of cardiovascular disease in women. Healthcare providers could be encouraged to implement established guidelines on the prevention of cardiovascular disease in women.

摘要

背景

多项研究表明,心血管危险因素和疾病的管理存在性别差异。法国心脏病专家在管理高血压方面是否存在性别差异尚未得到充分研究。

目的

本横断面、多中心研究的主要目的是检查法国门诊心脏病专家根据性别管理高血压患者的情况。

方法

要求心脏病专家连续纳入 2 名男性和 2 名女性因原发性高血压就诊的常规咨询患者。通过比较过去 6 个月的心血管检查和根据性别以及患者的整体心血管风险评估高血压控制情况,评估治疗管理。

结果

总体而言,对 654 名心脏病专家转诊的 3440 名成年患者(53%为男性)的数据进行了分析。男性和女性的高血压均未得到控制,分别为 76%和 76%,且 69%的患者存在高整体心血管风险(男性为 75%,女性为 62%;P<0.001)。在过去的 6 个月中,女性进行的心血管检查明显少于男性(22.6%比男性的 44.2%;P<0.001)。无论性别或整体心血管风险如何,大约有 50%的患者需要调整心血管治疗方案。

结论

PARITE 研究表明,在法国的门诊心脏病学实践中,女性和男性患者的降压方案调整频率相似。然而,结果表明,女性心血管疾病的检查仍有改进的空间。可以鼓励医疗保健提供者实施针对女性心血管疾病预防的既定指南。

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