Department of Medicine, Division of General Internal Medicine, Duke University, Durham, NC 27705, USA.
Am Heart J. 2012 Jun;163(6):980-6. doi: 10.1016/j.ahj.2012.03.016. Epub 2012 May 21.
Half of patients with hypertension have poor blood pressure (BP) control. Recent models for treating hypertension have integrated disease monitoring and telephone-based interventions delivered in patients' homes. This study evaluated the costs of the Hypertension Intervention Nurse Telemedicine Study (HINTS), aimed to improve BP control in veterans.
Eligible veterans were randomized to either usual care or 1 of 3 telephone-based intervention groups using home BP telemonitoring: (1) behavioral management, (2) medication management, or (3) combined. Intervention costs were derived from information collected during the trial. Direct medical costs (inpatient, outpatient, and outpatient pharmacy, including hypertension-specific pharmacy) at 18 months by group were calculated using Veterans Affairs (VA) Decision Support System data. Bootstrapped CIs were computed to compare intervention and medical costs between intervention groups and usual care.
Patients receiving behavior or medication management showed significant gains in BP control at 12 months; there were no differences in BP control at 18 months. In subgroup analysis, patients with poor baseline BP control receiving combined intervention significantly improved BP at 12 and 18 months. In overall and subgroup samples, average intervention costs were similar in the 3 study arms, and at 18 months, there were no statistically significant differences in direct VA medical costs or total VA costs between treatment arms and usual care.
To optimize investment in telephone-based home interventions such as the HINTS, it is important to identify groups of patients who are most likely to benefit from more intensive home BP management.
一半的高血压患者血压控制不佳。最近的高血压治疗模式整合了疾病监测和在患者家中进行的电话干预。本研究评估了旨在改善退伍军人血压控制的高血压干预护士远程医疗研究(HINTS)的成本。
符合条件的退伍军人被随机分配到常规护理或 3 种基于电话的干预组之一,使用家庭血压远程监测:(1)行为管理,(2)药物管理,或(3)联合。干预成本来自试验期间收集的信息。通过退伍军人事务部(VA)决策支持系统数据,计算了 18 个月时各组的直接医疗成本(住院、门诊和门诊药房,包括高血压特定药房)。使用 bootstrap 方法计算了干预组和常规护理组之间干预和医疗成本的置信区间。
接受行为或药物管理的患者在 12 个月时血压控制显著改善;在 18 个月时,血压控制没有差异。亚组分析显示,基线血压控制较差的患者接受联合干预在 12 个月和 18 个月时血压显著改善。在总体和亚组样本中,3 个研究组的平均干预成本相似,在 18 个月时,治疗组与常规护理组之间在直接 VA 医疗成本或总 VA 成本方面没有统计学上的显著差异。
为了优化基于电话的家庭干预(如 HINTS)的投资,重要的是要确定最有可能从更强化的家庭血压管理中受益的患者群体。