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银屑病关节炎中的免疫紊乱(作者译)

[Immunologic disturbances in psoriatic arthropathy (author's transl)].

作者信息

Sany J, Clot J, Guilhou J J, Serre H

出版信息

Sem Hop. 1979;55(23-26):1233-5.

PMID:227114
Abstract

It was observed in 51 cases of psoriatic arthropathy (PA) an increase of blood IgA and a decrease of IgM, a not significant rise of the level of circulating immune complexes, a positive Waaler-Rose reaction in 9.7% of cases and the presence of antigammaglobulin factors (generally of IgG type) in 55,5% of studied patients. Moreover, it was noted a significant decrease of T lymphocytes as detected by E and "active" E rosettes, of EA-gamma rosettes (ox erythrocytes) and an increase of the percentage of high avidity Fc-gamma receptor bearing cells. Lymphocytes responses to mitogens were normal or slightly decreased for Concanavalin A. No correlation was found between the immunological data and the clinical features.

摘要

在51例银屑病关节炎(PA)患者中观察到,血液中IgA升高、IgM降低,循环免疫复合物水平有不显著升高,9.7%的病例出现阳性瓦勒-罗斯反应,55.5%的研究患者存在抗球蛋白因子(一般为IgG型)。此外,通过E和“活性”E花环、EA-γ花环(氧化红细胞)检测发现T淋巴细胞显著减少,高亲和力Fc-γ受体阳性细胞百分比增加。淋巴细胞对植物血凝素的反应正常或稍有降低。免疫数据与临床特征之间未发现相关性。

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