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[银屑病中的淋巴细胞及其亚群]

[Lymphocytes and their subpopulations in psoriasis].

作者信息

Vignale R, Pereira A, Paciel J, Galbarini E

出版信息

Med Cutan Ibero Lat Am. 1984;12(3):193-8.

PMID:6384688
Abstract

Peripheral blood lymphocytes and his subpopulations from 32 psoriatic patients were analyzed. For this, E rosettes for T cells, EAC rosettes for B cells and EA rosettes for receptors for Fc-IgM and Fc-IgG on T cells were employed. A decrease of circulating T cells is demonstrated as well an increase of null cells. No differences are observed for the number of circulating TM to TG cells (with Fc-IgM or Fc-IgG receptors). However, a decreased of T null(T/) cells was found. The authors postulate that the phenotypic appearances of T cells was associated to localize waste of modulated or activated T cells in lesions during the active phase of psoriasis.

摘要

对32例银屑病患者的外周血淋巴细胞及其亚群进行了分析。为此,采用了检测T细胞的E花环、B细胞的EAC花环以及T细胞上Fc-IgM和Fc-IgG受体的EA花环。结果显示循环T细胞减少,裸细胞增加。循环中具有Fc-IgM或Fc-IgG受体的TM细胞与TG细胞数量未观察到差异。然而,发现T裸(T/)细胞减少。作者推测,在银屑病的活动期,T细胞的表型变化与皮损中经调节或活化的T细胞局部损耗有关。

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