Baryshnikov A Iu
Vestn Ross Akad Med Nauk. 2012(3):23-31.
Liposomes quite recently have turned from a model of biological membranes into an object of extensive research and practical use. The versatile traits of liposomal formulation allow its' universal implementation, especially in cancer chemotherapy. The advantages of liposomal use as a carrier of an anticancer drug for its targeted selective accumulation are discussed in this article. This article contains description of new types of liposomes, differing in contents and use, such as: simple, sterically stabilized, targeted (immunoliposomes),cationic, sensitive to physical and chemical stimuli. The characteristics of liposomal systems of anticancer drug delivery designed at Blokhin Russian Oncological Scientific Centre is given in the article.
脂质体最近已从生物膜模型转变为广泛研究和实际应用的对象。脂质体制剂的多种特性使其得以普遍应用，尤其是在癌症化疗中。本文讨论了脂质体作为抗癌药物载体用于靶向选择性积累的优势。本文介绍了新型脂质体，它们在成分和用途上有所不同，例如：简单型、空间稳定型、靶向型（免疫脂质体）、阳离子型、对物理和化学刺激敏感型。文章还给出了俄罗斯布罗欣肿瘤科学中心设计的抗癌药物递送脂质体系统的特点。
