Burakovskiĭ V I, Fal'kovskiĭ G E, Gorbachevskiĭ S V
Grud Serdechnososudistaia Khir. 1990(10):3-7.
The article discusses the appraisal of the degree of pulmonary hypertension and surgery of a ventricular septal defect with pulmonary hypertension in 108 patients whose ages ranged from 8 months to 31 years. The hemodynamic and morphological manifestations of pulmonary hypertension were found to increase with age. The hemodynamic manifestations of the anomaly may be similar in different types of changes of the vascular wall. A sharply hypertrophied middle muscular coat may be the cause of residual high pressure after closure of the defect, but with gradual reduction in contrast to the stable increase in sclerosis of the vascular lumen. This predetermines lung biopsy as an obligatory method for verifying the severity of pulmonary hypertension, which together with the hemodynamic data allows the indications for closure of the ventricular septal defect to be determined.
本文探讨了108例年龄在8个月至31岁之间的室间隔缺损合并肺动脉高压患者的肺动脉高压程度评估及手术情况。发现肺动脉高压的血流动力学和形态学表现随年龄增长而增加。不同类型血管壁改变时，该异常的血流动力学表现可能相似。明显肥厚的中层肌层可能是缺损闭合后残余高压的原因，但与血管腔硬化稳定增加相反，其会逐渐减轻。这决定了肺活检作为验证肺动脉高压严重程度的必要方法，其与血流动力学数据一起可确定室间隔缺损闭合的指征。
