Meshalkin E N, Litasova E E, Vlasov Iu A, Okuneva G N, Shishkina T N
Kardiologiia. 1979 Feb;19(2):20-5.
The results of direct pressure measurement in pulmonary circulation in 452 patients with ventricular septal defect (216 males and 236 females), whose age ranged from 12 months to 37 years, were analysed. The findings of diagnostic catheterization of the heart in 150 practically healthy persons 12 months to 40 years of age were used to elaborate the normal values of pressure in pulmonary circulation. The results of pressure measurement in pulmonary circulation repeated at intervals of 1 to 6 years in 46 patients with ventricular septal defect, 18 months to 23 years of age, were analysed. Reverse evolution of pressure in pulmonary circulation after surgical rehabilitation was followed up in 85 patients in 1, 2, 3, 5, and 7 years after the operation. At the age of 12 months to 7 years, systolic pressure in the right ventricle and pulmonary artery comes down to a possible minimum due to expenditure of the adaptational reserve. In large ventricular septal defects, however, the organism proves incapable of reducing the pressure in the early and first periods of childhood as a rule, and so the pressure increases throughout life.
分析了452例室间隔缺损患者（男216例，女236例）肺循环直接测压结果，患者年龄为12个月至37岁。利用150例年龄在12个月至40岁的健康人的心脏诊断性心导管检查结果，制定肺循环压力的正常值。分析了46例年龄在18个月至23岁的室间隔缺损患者每隔1至6年重复进行的肺循环压力测量结果。对85例患者术后1、2、3、5和7年肺循环压力手术后恢复的逆向演变进行了随访。在12个月至7岁时，由于适应性储备的消耗，右心室和肺动脉的收缩压降至可能的最低值。然而，在大型室间隔缺损中，通常在儿童早期和初期机体无法降低压力，因此压力会终生升高。
