Fedotovskikh G V, Potapov V A
Grud Serdechnososudistaia Khir. 1990(10):65-8.
The article deals with the clinico-morphological appraisal of bougienage and intubation of patients with cicatricial constriction of the esophagus after chemical burns. Endoscopic and morphological studies were carried out in 38 patients before and during treatment. Bioptic material collected from the esophageal mucosa was studied on a light-optic and ultrastructural level. The results of the study showed that bougienage of the epithelialized strictures causes protracted stimulation of intracellular regenerative processes and thus facilitates the development of leukoplakia of the squamous epithelium. The prevention of esophageal precancer in this case consists in radical maintenance bougienage and regular medical examination. Bougienage of ++non-epithelialized strictures stimulates the formation of young granulation tissue, while subsequent intubation stimulates reparative processes, creating in this manner conditions for adequate epithelialization of the ulcerated esophageal strictures.
本文探讨了化学烧伤后食管瘢痕性狭窄患者扩张及插管的临床形态学评估。对38例患者在治疗前及治疗期间进行了内镜和形态学研究。从食管黏膜采集的活检材料进行了光镜和超微结构水平的研究。研究结果表明，对已上皮化狭窄进行扩张会导致细胞内再生过程的长期刺激，从而促进鳞状上皮白斑的发展。在这种情况下预防食管癌前病变在于进行根治性维持扩张及定期医学检查。对未上皮化狭窄进行扩张会刺激年轻肉芽组织的形成，而随后的插管会刺激修复过程，以此为溃疡型食管狭窄的充分上皮化创造条件。
