Tsuchiya S, Narisawa K, Konno T, Tada K
Tohoku J Exp Med. 1979 Oct;129(2):105-10. doi: 10.1620/tjem.129.105.
Lymphoblastoid cell lines from a patient with adenosine deaminase (ADA) deficiency and his parents were established by Epstein-Barr virus (EBV). ADA activity in the lymphoblastoid cells from the patient was not detectable, while the enzyme activity in the cells from his parents was approximately a half level of the controls'. No inhibitor to ADA could be detected in the lymphoblastoid cells from the patient.
用爱泼斯坦-巴尔病毒(EBV)建立了一名腺苷脱氨酶(ADA)缺乏症患者及其父母的淋巴母细胞样细胞系。患者淋巴母细胞样细胞中的ADA活性无法检测到,而其父母细胞中的酶活性约为对照组的一半。在患者的淋巴母细胞样细胞中未检测到ADA抑制剂。