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由爱泼斯坦-巴尔病毒建立的来自一名腺苷脱氨酶缺陷患者的淋巴母细胞系。

A lymphoblastoid cell line from an adenosine deaminase deficient patient established by Epstein-Barr virus.

作者信息

Tsuchiya S, Narisawa K, Konno T, Tada K

出版信息

Tohoku J Exp Med. 1979 Oct;129(2):105-10. doi: 10.1620/tjem.129.105.

Abstract

Lymphoblastoid cell lines from a patient with adenosine deaminase (ADA) deficiency and his parents were established by Epstein-Barr virus (EBV). ADA activity in the lymphoblastoid cells from the patient was not detectable, while the enzyme activity in the cells from his parents was approximately a half level of the controls'. No inhibitor to ADA could be detected in the lymphoblastoid cells from the patient.

摘要

用爱泼斯坦-巴尔病毒(EBV)建立了一名腺苷脱氨酶(ADA)缺乏症患者及其父母的淋巴母细胞样细胞系。患者淋巴母细胞样细胞中的ADA活性无法检测到,而其父母细胞中的酶活性约为对照组的一半。在患者的淋巴母细胞样细胞中未检测到ADA抑制剂。

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